Results 81 to 90 of about 438,725 (309)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Innovation and Productivity across Four European Countries [PDF]

This paper compares the role innovation plays in productivity across the four European countries France, Germany, Spain and the UK using firm-level data from the internationally harmonized Community Innovation Surveys (CIS3).
Rachel Griffith, Elena Huergo, Jacques Mairesse, Bettina Peters   +3 more
core  

European Innovation Council's strategic actions: A game-changer for cell and gene therapy. [PDF]

Mol Ther, 2022
Arzimanoglou I.
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

INNOVATION PERFORMANCE IN EUROPEAN UNION [PDF]

The enlargement of the European Union calls for specific action to be taken. People in the candidate countries have often had to display a capacity for entrepreneurship in adapting to the transformation of their economies.
Irina Gabriela Radulescu
core  

European Innovation Scoreboard 2022

, 2022
The annual European Innovation Scoreboard (EIS) provides a comparativeassessment of the research and innovation performance of EU MemberStates and selected third countries, and the relative strengths andweaknesses of their research and innovation systems.
Hollanders, Hugo; id_orcid, Khalilova, Aishe, Es-Sadki, Nordine; id_orcid   +2 more
core   +1 more source

Resilient Regional Labour Markets as Triggers of Innovation Success during Crises: Perspective of EU Innovation Leaders

TalTech Journal of European Studies
Despite the growing interest in the impact of economic crises on regional labour markets, innovation, and regional resilience, the relationship between these economic aspects remains under-researched in the context of these crises.
Fišera Tomáš, Vaníček Bernard
doaj   +1 more source

Innovation Policy in European Union [PDF]

Theoretical and Applied Economics, 2006
The innovation policies aim to analyze priority factors shaping innovative performance and to reflect the increasing appreciation of the economic and social importance of innovation.
Marta-Christina Suciu
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

A European innovation ecosystem for social innovation

, 2018
Social innovation offers citizens and enterprises a means to engage in meaningful and beneficial activity. The EU has the potential to catalyse a much larger implementation of social innovation to address crucial challenges at European, national and local levels.
openaire   +2 more sources