Results 31 to 40 of about 2,273,648 (354)

EU and US External Policies on Human Rights and Democracy Promotion: Assessing Political Conditionality in Transatlantic Partnership [PDF]

open access: yesRomanian Journal of European Affairs, 2015
This contribution aims at advancing existing research about the role that the Transatlantic Partnership may play within the specific field of human rights and democracy promotion in the current changing global order.
Beatriz Pérez de las Heras
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE EUROPEAN UNION AND THE ‘NEW WAR’ FROM ITS EASTERN BORDERS [PDF]

open access: yesEURINT, 2016
There is enough evidence to claim that since 2014 a new type of war is waged in Ukraine, which is novel in terms of methods, strategies, tactics, and level of human sacrifice.
Miruna TRONCOTĂ
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The Changing Unpolitics of Covid‐19 Vaccine Procurement

open access: yesPolitics and Governance
Populist governments engage in “unpolitics” when the electoral incentives for doing so outweigh the distributive risks from policy failure. Studying the joint procurement of vaccines against Covid-19, I show that a group consisting of mostly populist ...
Henning Deters
doaj   +1 more source

NEW TENDENCIES REGARDING SAME-SEX MARRIAGE IN THE MEMBER STATES OF THE EUROPEAN UNION: – A BRIEF INSIDE AND OUTSIDE PERSPECTIVE – [PDF]

open access: yesChallenges of the Knowledge Society, 2013
Sexual orientation discrimination has been recently outlined within the Plenary Session of the European Parliament that took place in Brussels, on 24th May 2012 as a priority in the fight against discrimination of all kind, making a “call on EU member ...
JONE-ITXARO ELIZONDO   +1 more
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

What is governance in global telecoupling?

open access: yesEcology and Society, 2019
The concept of telecoupling is increasingly used as a framework to understand globally distant interconnections and their sustainability implications.
Jens Newig   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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