Results 31 to 40 of about 2,604,944 (359)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Examining the relation between education, recidivism & crime prevention

open access: yesDiscover Global Society
This article examines the relation between education in prisons and the reduction of recidivism, assessing the potential benefits of prison education and vocational programs at an international scale.
Georgios Chloupis, Despoina Kontompasi
doaj   +1 more source

OPTIONS FOR MONITORING OF SPACES PUBLICLY INACCESSIBLE IN THE CONTEXT OF PROTECTION OF PERSONAL DATA AND PERSONAL RIGHTS

open access: yesInternational Journal of Entrepreneurial Knowledge, 2018
  The submitted article devotes to the protection of personal data, the protection of personal rights in connection to the use of monitoring devices – camera systems.
Zuzana KURUCOVÁ, Marcela TITTLOVÁ
doaj   +1 more source

Defending the Rights of the Victims of Corruption in the Republic of Kosovo: With a Special Focus to the Pandemic Covid-19

open access: yesSEEU Review, 2020
Justice is not only about punishing the perpetrators but also protecting the rights of their victims. Corruption is not a victimless crime! Therefore, the main intention of this paper is to enlighten that protecting the rights of the victims of ...
Ibrahimi Adrianit, Arifi Besa
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The New European Choice-Of-Law Revolution [PDF]

open access: yes, 2008
Conflict of laws in Europe was long viewed by outsiders as formalist, antiquated, and uninteresting. Now that the European Union has become more active in the field, things are changing, but most view these changes as a mere gradual evolution.
Michaels, Ralf
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Legal Autonomy vs. Political Power: What is the Role of the European Court of Justice in the European Integration? [PDF]

open access: yesRomanian Journal of European Affairs, 2007
The European Court of Justice, founded as one of the main institutions of the European Union, has greatly contributed to further deepen the integration process. At the same time, the ECJ is one of the most controversial institutions.
Rufat R. Babayev
doaj  

Prevalence, Determinants, and Outcomes of Low Disease Activity and Remission Attainment in Patients With Systemic Lupus Erythematosus That Is Clinically Active

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to identify in patients with systemic lupus erythematosus (SLE) with clinically active disease the attainment of frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS) and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao   +39 more
wiley   +1 more source

The Creative Economy Through the Lens of Urban Resilience. An Analysis of Romanian Cities

open access: yesTransylvanian Review of Administrative Sciences, 2020
The creative economy has attracted increasing attention from academia and policymakers for more than two decades. However, despite the flourishing literature on this topic, its complex connection with development and its role in strengthening resilience ...
Sorin Mazilu   +2 more
doaj   +1 more source

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