Results 121 to 130 of about 73,173 (211)

Impact of regulatory measures on the approval timelines of advanced therapy medicinal products by the European Medicines Agency. [PDF]

Front Med (Lausanne)
Alaburde S, Ivaska J, Kaspute G, Ivaskiene T.   +3 more
europepmc   +1 more source

For the European Medicines Agency, A Decade of Challenges [PDF]

JNCI: Journal of the National Cancer Institute, 2005
openaire   +1 more source

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

Real-World Evidence in Drug Approvals at the European Medicines Agency.

JAMA Netw Open
Bachinger M, Jankowski MA, Kesselheim AS, Krüger N.   +3 more
europepmc   +1 more source

Defending scientific integrity through collaboration: the European Medicines Agency and <i>The Lancet Regional Health - Europe</i>. [PDF]

Lancet Reg Health Eur
The Lancet Regional Health-Europe.
europepmc   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Methodological Insights on Biomarker-Based Patient Selection: A Review of Scientific Advice Procedures at the European Medicines Agency. [PDF]

Clin Pharmacol Ther
Huber C, Zinserling J, Benda N, Vetter T, Rueckbeil M.   +4 more
europepmc   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

Advanced Materials Interfaces, EarlyView.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda, Aldo Roberto Boccaccini, Irem Unalan   +2 more
wiley   +1 more source

The European Medicines Agency and <i>The Lancet Regional Health</i>-<i>Europe</i> join forces to protect public health. [PDF]

Lancet Reg Health Eur
Burgos JG, Thirstrup S, Cooke E.
europepmc   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source