Results 41 to 50 of about 644,498 (301)

Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.) [PDF]

open access: yesRomanian Journal of European Affairs, 2013
The volume “Lobbying the European Union: Institutions, Actors and Issues”, collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying – the existing relations between the EU institutions and the ...
Alexandra Pop
doaj  

The European Council [Copenhagen Summit 1978], Copenhagen, 7-8 April 1978 [PDF]

open access: yes, 1978
Dossier: Conclusions, statement by European Parliament President Emilio Colombo, statement by European Commission President Roy Jenkins, article on Community-Japanese ...

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Energy – Adjusting to a New Global Order

open access: yesCadmus, 2022
Globalization was challenged by the context of the COVID-19 pandemic, which forced the European Union to acknowledge its limitations on many fronts, from access to raw materials to manufacturing, and from control of data to innovation in general.
Maria da Graça Carvalho
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

MULTILINGUALISM AT THE COURT OF JUSTICE OF THE EUROPEAN UNION: THEORETICAL AND PRACTICAL ASPECTS

open access: yesStudies in Logic, Grammar and Rhetoric, 2013
The paper analyses and evaluates the linguistic policy of the Court of Justice of the European Union against the background of other multilingual courts and in the light of theories of legal interpretation.
Łachacz Olga, Mańko Rafał
doaj   +1 more source

The Right to Healthcare in the European Union and Canada: The Role of the Centre in Complex Entities

open access: yesCroatian Yearbook of European Law and Policy, 2019
The right to healthcare is a socio-economic right. It is positive in the sense that governments need to provide resources and set the priorities for individuals to be able to exercise it. The provision of healthcare within complex political entities such
Tomislav Sokol
doaj   +1 more source

International Civil Responsibility for the Epidemics Outbreak: COVID-19 as a Model

open access: yesZanco Journal of Humanity Sciences, 2020
This research deals with the extent to which civil state responsibility for epidemic diseases can be held. A special focus will be on the Covid-19 pandemic that originated in the People's Republic of China, as a model of a case study. To achieve the aim,
Ayad Yasin Husein Kokha   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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