Results 81 to 90 of about 40,583 (252)

MARTINGALES AND PARTIAL DIFFERENTIAL EQUATIONS PRICE VALUATION MODELS FOR EUROPEAN PUT OPTIONS

In financial mathematics, options are seen as financial transactions that gives the holder the right rather than obligations to buy or sell some specific quantity of an asset in the eminent future at a static price often called the strike price on or before the expiration date of the option contract.
Hamilton C. Chinwenyi, Hussaini D. Ibrahim and Theophilus Danjuma   +1 more
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

A Numerical Analysis of Comparing Several Practical Approaches for Pricing both American and European Put Options

AIUB Journal of Science and Engineering (AJSE)
The present paper focuses on pricing with European or American put option that has yet to be studied. In solving option pricing problems, numerical methods form an essential part. Five numerical methods: Black-Scholes-Merton, Monte Carlo, Binomial, Trinomial, and Finite Difference have been implemented in the present work. Here Computer Algebra System (
Afroza Akter, A B M Shahadat Hossain, Salma Parvin   +2 more
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis of Options Contract, Option Pricing in Agricultural Products

مجله اقتصاد و توسعه کشاورزی, 2016
Introduction: Risk is an essential component in the production and sale of agricultural products. Due to the nature of agricultural products, the people who act in this area including farmers and businesspersons encounter unpredictable fluctuations of ...
H. Tamidy, H. Mohammadi, D. Seify Gharhitaq, V. Dehbashi   +3 more
doaj  

The Artificial Intelligence and the dispute for different ways in its predictive use in the criminal process

Revista Brasileira de Direito Processual Penal, 2019
The article explores the dispute between two global models about the acceptance of artificial intelligence to carry out predictive research around judges and courts, with special focus on criminal procedures.
Rodrigo Régnier Chemim Guimarães
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

De la istorie naţională la istorie europeană în şcolile româneşti (From National to European History in Romanian Schools) [PDF]

Polis: Revista de Stiinte Politice, 2016
As of 1989, Romania officially separated itself from communism, expressing its option for democracy. This meant a new change of paradigm, in which education for democracy and European values (Romania expressing its wish to join the European Union) were ...
Emilian COLCERU-MIHUL
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source