Results 231 to 240 of about 3,155,757 (335)

Mutations in GFAP Alter Early Lineage Commitment of Organoids

open access: yesGlia, EarlyView.
Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on the method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. Graphical abstract was created with BioRender.com .
Werner Dykstra   +14 more
wiley   +1 more source

AAV‐Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone‐Induced Demyelination

open access: yesGlia, EarlyView.
AAV‐BDNF improves cognitive performance after cuprizone‐induced de‐myelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology. ABSTRACT Multiple sclerosis (MS) is a chronic neurological disorder involving immune‐mediated demyelination
Yousra El Ouaamari   +14 more
wiley   +1 more source

Culturomics Profiling of Nasal Cavities of European Wild Rabbits on the Iberian Peninsula: Antimicrobial Resistance and Detection of Microorganisms of Public Health Interest [PDF]

open access: gold
Carmen González‐Azcona   +11 more
openalex   +1 more source

The anti‐aging Klotho protects glioblastoma macrophages from radiotherapy‐induced inflammation and predicts immunotherapy response

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo   +19 more
wiley   +1 more source

Tick-wildlife host-pathogen network interactions in Northern Africa. [PDF]

open access: yesPLoS One
Rafael M   +8 more
europepmc   +1 more source

Biological evaluation of a glucose‐based boron carrier as a potential agent for boron neutron capture therapy

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Boron neutron capture therapy (BNCT) is a targeted form of radiation therapy designed to selectively destroy cancer cells. BNCT is not widely used, however, owing in part to challenges involving selective boron delivery to tumors. The present study evaluated the potential of a novel glucoconjugate, 6‐O‐(o‐carboranylmethyl)‐d‐glucopyranose ...
Surachet Imlimthan   +15 more
wiley   +1 more source

Updated peer review of the pesticide risk assessment of the active substance fosetyl. [PDF]

open access: yesEFSA J
European Food Safety Authority (EFSA)   +48 more
europepmc   +1 more source

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