Results 41 to 50 of about 19,861,190 (287)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The First Pan-European Sociological Health Inequalities Survey of the General Population: The European Social Survey Rotating Module on the Social Determinants of Health [PDF]
European Sociological Review, 2016 The European Social Survey (ESS) is a biennial, academically driven, cross-sectional, pan-Europeansocial survey that charts and explains the interactions between Europe’s changing institutions and theattitudes, beliefs, and behaviour patterns of its diverse populations. As part of the seventh round ofthe ESS, we successfully developed a rotating module
TA Eikemo +3 more
openaire +5 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Tér és Társadalom, 2020 A tanulmány kiindulópontja az, hogy a koronavírus miatti járvány fokozottan érinthették azokat, akik már a krízisperiódus előtt is fizikai/lelki egészségi problémákkal küzdöttek, társas kapcsolataikat tekintve elszigeteltek voltak, és/vagy az anyagi ...
Grünhut Zoltán, Bodor Ákos
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2021 Survey data is used in many social science studies. The measurement quality of these data is crucial as it determines the accuracy of the information on which these studies are based.
Asensio, Marc +4 more
core +1 more source
Наукові Записки Наукма: Соціологія, 2019 В основу статті покладено аналіз впливу соціальної нерівності на здоров’я українського населення віком 18–65 років на базі масиву даних European Social Survey 2012 року (N = 2178) з використанням статистичного пакета SPSS. Авторські знахідки узгоджуються
Daria Mazay, Kateryna Maltseva
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source