CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
European standard internal telephone number 2222 for in-hospital emergency calls: A national survey in all French military training hospitals. [PDF]
Py N +10 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Strength conditions for wheel/rail system according with European standard EN 13001-3.3 [PDF]
The European Standard EN 13001 was prepared by CEN/TC-147/WG 2 Cranes. Design - General”, where author of this article is one of the members of the international working group.
Sylwester MARKUSIK
doaj
Comparison of the in-vitro efficacy of different mouthwash solutions targeting SARS-CoV-2 based on the European Standard EN 14476. [PDF]
Steinhauer K +10 more
europepmc +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A Methodology for the Multi-Point Characterization of Short-Term Temperature Fluctuations in Complex Microclimates Based on the European Standard EN 15757:2010: Application to the Archaeological Museum of L'Almoina (Valencia, Spain). [PDF]
Díaz-Arellano I +3 more
europepmc +1 more source
Quality standards for passenger trains: Political majorities and environmental costs [PDF]
This study analyzes the minimum quality standard set by the European Union (EU) through Regulation 1371/2007 of Rail Passengers' Rights and Obligations. A welfare maximizing quality standard raises quality and consumer satisfaction, but does not improve ...
Rothbauer, Julia, Sieg, Gernot
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Safety system installation on the underground gas storages wells of Nafta a.s. [PDF]
Increasing of safety operation underground gas storage wells requires to install safety system on this wells to be protected against unwarranted activity. It is in correspondence with recommendation of European Standard EN 1918 1-5.
Doek Ján +2 more
doaj

