Results 121 to 130 of about 4,717,805 (303)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
The use of ICT tools by academic teachers in the international comparative context [PDF]
, 2019 The article sets out to analyze the professional competencies on the standard European e-Competence Framework. The survey of information technology teachers of Ukrainian universities concerning the necessity of forming and development of European e ...
Cubo-Delgado, S +4 more
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Repair Composite Adhesion Strength: A Comparison of Testing Methods
Applied SciencesThe adhesive strength of repair composites to concrete substrates was assessed through both Ukrainian and European standard test methods. The types of adhesion loss observed included adhesive failure along the contact layer (AF-S), and cohesion failure ...
Khrystyna Moskalova +3 more
doaj +1 more source
Macroeconomic and policy uncertainty and Exchange rate risk Premium [PDF]
The goal of this paper is to identify the main determinants of the risk premium in some European currency markets just before the EMU. To that extent, we start from Lucas (1982) exchange rate model and derive an analytical expression for the forward ...
Juan-Ángel Jiménez-Martín +1 more
core
Labour adjustment in agriculture: Assessing the heterogeneity across transition countries [PDF]
, 2011 A standard model of labour adjustment in times of economic transition assumes a constant impact of variables like sectoral income differences, unemployment or the relative size of the agricultural sector.
Dries, L.K.E., Glauben, T., Herzfeld, T.
core +1 more source
(N+1)-dimensional Lorentzian evolving wormholes supported by polytropic matter
, 2013 In this paper we study $(N+1)$-dimensional evolving wormholes supported by energy satisfying a polytropic equation of state. The considered evolving wormhole models are described by a constant redshift function and generalizes the standard flat Friedmann-
Arostica, Fernanda +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The European standard-norm and the linguistic change in Mozambican school
Gragoatá, 2012 In Mozambique, the portuguese language is considered the official language, second language, national language and competes with more than twenty Bantu languages spoken by the majority of population.
Alexandre António Timbane +1 more
doaj