Results 111 to 120 of about 6,018,247 (397)

European Union [PDF]

The European Community has had a decidedly significant impact upon the legal systems of the Member States. It was established in 1957 by the Treaty of Rome, the main objectives being to develop stability throughout Europe by means of encouraging a closer
Jomadar, Dinesh
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

ACL injury prevention in European women’s football: exploring knowledge, attitudes and practices in a cross-sectional study

BMJ Open Sport & Exercise Medicine
Objective To assess the knowledge, attitudes and behaviours regarding anterior cruciate ligament (ACL) injury prevention among individuals involved in women’s football at all levels, including players and staff across Union of European Football ...
Evert Verhagen, Katrine Okholm Kryger, Gabriel Monthuley   +2 more
doaj   +1 more source

The Electrochemical and Statistical Evaluation of Isolation of Mellitin and Apamin from Honey Bee (Apis Mellifera) Venom

International Journal of Electrochemical Science, 2015
We present in this manuscript for the first time the electrochemical and statistical evaluation of FPLC isolation of mellitin and apamin from honey bee (Apis mellifera) venom. Venoms are extremely complex blends of diverse substances that target a myriad
Hoai Viet Nguyen, Zbynek Heger, Marketa Kominkova, Petr Michalek, Jaromir Gumulec, Roman Guran, Antonin Pridal, Carlos Fernandez, David Hynek, Vojtech Adam, Rene Kizek   +10 more
doaj   +1 more source

The Policy Effect of the General Data Protection Regulation (GDPR) on the Digital Public Health Sector in the European Union: An Empirical Investigation

International Journal of Environmental Research and Public Health, 2019
The rapid development of digital health poses a critical challenge to the personal health data protection of patients. The European Union General Data Protection Regulation (EU GDPR) works in this context; it was passed in April 2016 and came into force ...
B. Yuan, Jiannan Li
semanticscholar   +1 more source

Foreign Labor Trends: European Union [PDF]

, 2003
Foreign Labor Trendseuropean_union_2003.pdf: 420 downloads, before Oct.
Bureau of International Affairs, U.S.
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Femtogram Electroanalytical Detection of Prostatic Specific Antigen by Brdicka Reaction

International Journal of Electrochemical Science, 2012
Prostatic-specific antigen is considered as the best marker for prostate cancer. Due to the importance of PSA for diagnostic purposes it is not surprising that there are tested and optimized various methods for its determination.
David Hynek, Sona Krizkova, Ludmila Krejcova, Jaromir Gumulec, Marketa Ryvolova, Natalia Cernei, Michal Masarik, Vojtech Adam, Libuse Trnkova, Marie Stiborova, Tomas Eckschlager, Jaromir Hubalek, Rene Kizek   +12 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Introduction: the European Union beyond the polycrisis? Integration and politicization in an age of shifting cleavages

The European Union Beyond the Polycrisis?, 2019
Over the past decade, the EU has faced multiple crises. In the introduction to this collection, we argue that this ‘polycrisis’ is fracturing the European political system across multiple, simultaneous rifts, thereby creating a ‘polycleavage’.
J. Zeitlin, F. Nicoli, Brigid Laffan
semanticscholar   +1 more source