Results 131 to 140 of about 6,113,935 (350)

The European Union: A Comparative Perspective [PDF]

open access: yes, 2016
This chapter, to be included in the Oxford Principles of EU Law volume, compares the federalisms of Europe and the United States. It argues that Europe can be sensibly viewed from both federal and intergovernmental perspectives, and that particular ...
Young, Ernest A.
core   +1 more source

Introduction: the European Union beyond the polycrisis? Integration and politicization in an age of shifting cleavages

open access: yesThe European Union Beyond the Polycrisis?, 2019
Over the past decade, the EU has faced multiple crises. In the introduction to this collection, we argue that this ‘polycrisis’ is fracturing the European political system across multiple, simultaneous rifts, thereby creating a ‘polycleavage’.
J. Zeitlin, F. Nicoli, Brigid Laffan
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Electrochemical Study of Doxorubicin Interaction with Different Sequences of Double Stranded Oligonucleotides, Part II

open access: yesInternational Journal of Electrochemical Science, 2012
Interaction of low molecular weight compounds with DNA is one of general mechanisms utilized for an effective anticancer therapy. The anthracycline doxorubicin is one of the drugs that represent the compound with such effect.
David Hynek   +9 more
doaj   +1 more source

Implications of Widening the European Union [PDF]

open access: yes, 1994
The article looks at the initial stated requirements for EU membership- that a Member State of the European Communities be “a European state”- and the implications of widening EU membership in light of additional requirements that have since been ...
Schloh, Bernhard
core   +1 more source

Brexit: Viable options to avoid crisis [PDF]

open access: yes, 2020
This paper covers the viable options that the United Kingdom may take to avoid economic and political crisis as they exit the European Union. There are several benefits and detriments to the exit. Some benefits include economic and political freedom from
Diercks, Samuel
core   +1 more source

The Policy Effect of the General Data Protection Regulation (GDPR) on the Digital Public Health Sector in the European Union: An Empirical Investigation

open access: yesInternational Journal of Environmental Research and Public Health, 2019
The rapid development of digital health poses a critical challenge to the personal health data protection of patients. The European Union General Data Protection Regulation (EU GDPR) works in this context; it was passed in April 2016 and came into force ...
B. Yuan, Jiannan Li
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Effect of Different Doses of Organically Bound Selenium on Antioxidant Status and Levels of Metal Ions in Postpartum Sows

open access: yesInternational Journal of Electrochemical Science, 2013
The study was focused on the effect of different doses of organically bound selenium on antioxidant status in postpartum sows. 24 sows, Large White (English Large White) breed were divided into three balanced groups.
Pavel Horky   +10 more
doaj   +1 more source

Productivity comparisons: the european union agriculture [PDF]

open access: yes, 1998
This paper ail11s at l11easuring the total factor productivity (TFP) of the European agricultural finns. With a Translog index, an interspatial comparison of tIle twelve European countries and intertel11poral productivity variations are computed to ...
Decimavilla Herrero, Esther   +1 more
core   +1 more source

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