Results 131 to 140 of about 6,018,247 (397)

Productivity comparisons: the european union agriculture [PDF]

open access: yes, 1998
This paper ail11s at l11easuring the total factor productivity (TFP) of the European agricultural finns. With a Translog index, an interspatial comparison of tIle twelve European countries and intertel11poral productivity variations are computed to ...
Decimavilla Herrero, Esther   +1 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Electrochemical Study of Doxorubicin Interaction with Different Sequences of Single Stranded Oligonucleotides, Part I

open access: yesInternational Journal of Electrochemical Science, 2012
Doxorubicin is a known anticancer drug intercalating into dsDNA. The mechanism of interaction of doxorubicin with ssDNA is not clear. In this study, adsorptive transfer stripping technique coupled with square wave voltammetry was used for studying of ...
David Hynek   +9 more
doaj   +1 more source

Implications of Widening the European Union [PDF]

open access: yes, 1994
The article looks at the initial stated requirements for EU membership- that a Member State of the European Communities be “a European state”- and the implications of widening EU membership in light of additional requirements that have since been ...
Schloh, Bernhard
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Electrochemical Study of Doxorubicin Interaction with Different Sequences of Double Stranded Oligonucleotides, Part II

open access: yesInternational Journal of Electrochemical Science, 2012
Interaction of low molecular weight compounds with DNA is one of general mechanisms utilized for an effective anticancer therapy. The anthracycline doxorubicin is one of the drugs that represent the compound with such effect.
David Hynek   +9 more
doaj   +1 more source

How media shape political trust: News coverage of immigration and its effects on trust in the European Union

open access: yesEuropean Union Politics, 2019
Attitudes towards immigration are among the core predictors of attitudes toward the European Union. However, even though most citizens learn about immigration through the media, we lack a comprehensive account of how media coverage of immigration ...
Anna Brosius   +2 more
semanticscholar   +1 more source

The role of African Union law in integrating Africa [PDF]

open access: yes, 2015
This article traces how the development of regional law is linked to the state of regional integration in Africa. Given the prominent role European Union law plays in the functioning of the European Union, the question is posed whether there is similar ...
Olivier, Michele, Olivier, Michèle E.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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