Results 251 to 260 of about 5,919,167 (410)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

open access: yesAdvanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen   +5 more
wiley   +1 more source

The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2024. [PDF]

open access: yesEFSA J
European Food Safety Authority (EFSA)   +7 more
europepmc   +1 more source

Micromechanical Characterization of 316L‐V4E Steel Transitions Produced by Electron Beam Powder Bed Fusion with Dual‐Hopper Alternating Layer Strategy

open access: yesAdvanced Engineering Materials, EarlyView.
This work applies High‐Speed Nanoindentation to study multi‐material transitions in powder bed fusion–electron beam melting components. The aim is to assess the mechanical gradients and interfacial behavior between American iron and steel institute 316L stainless steel and V4E tool steel in additively manufactured structures.
Laia Ortiz‐Membrado   +6 more
wiley   +1 more source

European Union, 2015

open access: yesAdministration, 2015
Malone Margaret Mary
doaj   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

open access: yesAdvanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes   +4 more
wiley   +1 more source

A comprehensive assessment of the existing landscape of personalized cancer medicine in the European Union, on behalf of the PCM4EU consortium. [PDF]

open access: yesESMO Open
Haj Mohammad SF   +18 more
europepmc   +1 more source

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