Results 41 to 50 of about 38,153 (292)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
O presente artigo busca analisar o atual processo de expansão do bloco europeu, tendo como foco seus rumos e conseqüências, tanto para a União Europeia em si, quanto para cada país individualmente.
Estevão Chaves de Rezende Martins
doaj
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
O presente artigo busca analisar os rumos e direcionamento do processo de expansão da União Europeia.
João Fábio Bertonha
doaj
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
A incorporação dos novos países à União Européia
O presente artigo busca delinear as conseqüências e impactos da expansão dos número de países integrantes do Bloco Europeu.
Miriam Gomes Saraiva
doaj
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
Foreign market selection process as tool for international expansion: Case study for ecuadorian chia seeds exports to the european union [PDF]
Eduardo Terán-Yépez+3 more
openalex +3 more sources
The Silk Road: consequences for the Eurasian Economic Union and European Union [PDF]
The article discloses possible consequences of the Chinese project of creating the Silk Road Economic Belt for the Eurasian Economic Union and European Union with recommendations for Russian authorities on conducting the policy that would allow to ...
Bazhan A.
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source