Results 171 to 180 of about 1,203,088 (377)

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

open access: yesAdvanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan   +11 more
wiley   +1 more source

A aplicabilidade direta do direito da União Europeia no direito interno

open access: yesRevista Interdisciplinar de Direito, 2012
The direct applicability of Community law over several decades has been a controversial topic in relation to the law of the member states. European Communities passed to the European Union, because the Lisbon Treaty is now able to speak only of a ...
Maria Manuela Magalhães Silva
doaj  

2D Programmable Photodetectors Based on WSe2/h‐BN/Graphene Heterojunctions

open access: yesAdvanced Science, EarlyView.
A programmable non‐volatile bipolar semi‐floating gate photovoltaic photodetector is developed, enabling reversible light response switching and improved response speed. This capability facilitates the successful implementation of the device in dual‐channel optoelectronic hybrid communication, fulfilling the performance demands of high‐speed, large ...
Zhihao Wang   +12 more
wiley   +1 more source

Wonders of Harbor and Grey Seal Whiskers: Morphology, Natural Frequencies, and 3D Modeling

open access: yesAdvanced Science, EarlyView.
Seals detect prey by sensing vortices using whiskers. How whisker morphologies and locations respond to hydrodynamic signals across various frequencies remains unclear. This study measures whiskers’ natural frequencies and morphologies and maps them to whisker locations on the muzzle, providing insights into how seals interpret hydrodynamic signals ...
Xingwen Zheng   +4 more
wiley   +1 more source

An Alignment Between the CRA's Essential Requirements and the ATT&CK's Mitigations [PDF]

open access: yesarXiv
The paper presents an alignment evaluation between the mitigations present in the MITRE's ATT&CK framework and the essential cyber security requirements of the recently introduced Cyber Resilience Act (CRA) in the European Union. In overall, the two align well with each other.
arxiv  

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

open access: yesAdvanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia   +12 more
wiley   +1 more source

The Legal Order of the European Community - A New Legal Typology

open access: yesActa Universitatis Danubius: Administratio, 2017
In order to fit the new European legal order on the legal map of the world, we intend to focus on the legal order of the European Union. The paper seeks to answer the questions: is the law of the European Union a new type of law with specific ...
Georgeta Modiga, Andreea Miclea
doaj  

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