Results 91 to 100 of about 9,735,164 (257)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Changing Value Systems in the new European Union [PDF]

, 2007
This working paper examines changing value systems in the new European Union with a special focus on religiosity and tolerance. We found that few of the new E.U. members brought particularly intense religiosity into the Union.
Webster, Craig., Yesilada, Birol A.,, Noordijk, Peter,   +2 more
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

The European Transformation of Modern Turkey. CEPS Paperback. September 2004 [PDF]

, 2004
The outcome of a research project carried out by CEPS and the Economics and Foreign Policy Forum (EFPF) of Istanbul, this book examines in detail the challenges and opportunities that would arise with Turkey’s full membership of the European Union.
Ülgen, Sinan, Emerson, Michael, Gros, Daniel, Derviş, Kemal   +3 more
core  

Effects of Traffic Loads on Road Bridges - Preliminary Studies for the Re-Asessment of the Traffic Load Model for Eurocode 1, Part 3. [PDF]

, 2012
2nd European Conference on Weigh-in-Motion of Road Vehicles, Lisbon, 14th - 16th September, 1998, European Commission, LuxembourgWIM has developed greatly in the last ten years and confidence in the accuracy of recorded data has increased significantly.
O\u27Brien, Eugene J., Jacob, Bernard, O'Brien, Eugene J., O'Connor, Alan, Prat, Michel, O\u27Connor, Alan   +5 more
core   +1 more source

The work of Ukrainian and Polish writers in the context of the literary process of the 19th century (using the example of the work of Olga Kobylianska and Eliza Ożeszko)

Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Ìсторія України. Українознавство: історичні та філософські науки
Research aim. The article attempts to elucidate the peculiarities of artistic modeling of female characters in the works of Olha Kobylianska and Eliza Orzeszkowa in the context of the Ukrainian-Polish literary dialogue of the nineteenth century ...
Natalia Demchenko, Anna Chala, Darya Yaitska   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Czech Republic and "Measures" of EU towards Austria in 2000

Czech Journal of International Relations, 2007
The paper analyses the motivation behind the Czech Foreign Policy's decision to support the "measures" of the "EU-14" towards Austria in 2000, which was an exception among EU-accessions candidate states.
Dagmar Moravcová
doaj  

Restoring Social Order Through Justice: The Social Dimension of Post-War Ukraine

Філософія освіти
The article explores the issue of identifying a concept of justice that could serve as the foundation for the socio-political organization of post-war Ukraine.
Тетяна Подольська, Андрій Лиманський   +1 more
doaj   +1 more source