Results 91 to 100 of about 69,559 (248)

Health-related quality of life in KEYNOTE-010 : a phase II/III study of pembrolizumab versus docetaxel in patients with previously treated advanced, programmed death ligand 1-expressing NSCLC

, 2019
Introduction: In the phase II/III KEYNOTE-010 study (ClinicalTrials.gov, NCT01905657), pembrolizumab significantly prolonged overall survival over docetaxel in patients with previously treated, programmed death ligand 1-expressing (tumor proportion score
Ahn, Myung-Ju, Barlesi, Fabrice, de Castro, Gilberto, Jr., Deitz, Anne C., Felip, Enriqueta, Fidler, Mary Jo, Garon, Edward B., Gubens, Matthew A., Han, Ji-Youn, Herbst, Roy S., Kim, Dong-Wan, Kim, Joo-Hang, Li, Qiao, Lubiniecki, Gregory M., Surmont, Veerle   +14 more
core   +1 more source

Impact of night-time symptoms in COPD : a real-world study in five European countries [PDF]

, 2013
Peer reviewedPublisher ...
Estruch, Jordi, Gil, Esther Garcia, Higgins, Victoria, Milligan, Gary, Price, David, Small, Mark   +5 more
core   +2 more sources

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

Improving valuation sampling of EQ-5D health states

Health and Quality of Life Outcomes, 2013
Background The original valuation exercise which formed the basis of the UK EQ-5D time trade-off social tariff of health states, employed a sampling scheme involving 43 health states.
Bagust Adrian
doaj   +1 more source

Association between upper extremity dysfunction and sleep disturbance in an elderly general population

SAGE Open Medicine, 2020
Objective: Several upper extremity disorders are associated with sleep disturbance in patient populations. This study evaluated the relation between self-assessment of upper extremity function and sleep disturbance in an elderly general population ...
Tsuyoshi Tajika, Takuro Kuboi, Fumitaka Endo, Satoshi Shinagawa, Hiroki Kobayashi, Shogo Hashimoto, Hideo Sakane, Noritaka Hamano, Tsuyoshi Sasaki, Tsuyoshi Ichinose, Hitoshi Shitara, Hirotaka Chikuda   +11 more
doaj   +1 more source

Patient‐reported health‐related quality of life in previously untreated chronic lymphocytic leukaemia: Results from the randomised phase 3 FLAIR trial comparing ibrutinib–rituximab versus fludarabine–cyclophosphamide–rituximab

British Journal of Haematology, EarlyView.
Summary Front‐Line therapy in CLL: Assessment of Ibrutinib‐containing Regimens (FLAIR) demonstrated improved progression‐free survival for ibrutinib and rituximab (IR) compared with fludarabine, cyclophosphamide and rituximab (FCR) in previously untreated chronic lymphocytic leukaemia (CLL).
David J. Allsup, David A. Cairns, E. Faye Samy, Lelia Duley, Adrian Bloor, Abraham Varghese, David Meads, Bryony Dawkins, Sean Girvan, Dena R. Howard, Anna Hockaday, Julia M. Brown, Sharon Jackson, Natasha Greatorex, Phoebe Templeton, Michael Tupper, David Phillips, Sonam Yaqub, Di Mortimer, David Stones, Piers E. M. Patten, Andrew Rawstron, Peter Hillmen, Talha Munir   +23 more
wiley   +1 more source

How do Zimbabweans value health states? [PDF]

, 2003
Background Quality of life weights based on valuations of health states are often used in cost utility analysis and population health measures. This paper reports on an attempt to develop quality of life weights within the Zimbabwe context. Methods 2,384
A Bowling, A Holmes, A Tsuchiya, AK Wagner, C Barker, Central Statistical Office, CJL Murray, E Nord, E Nord, Genstat, George W Torrance, GK Smyth, HME van Agt, J Jelsma, J Jelsma, J Jelsma, J Jelsma, Jennifer Jelsma, Kristian Hansen, M Bala, M Essink-Bot, NJ Devlin, P Dolan, P Kind, Paul de Cock, Paul Kind, PFM Krabbe, R Brooks, R Brooks, R Elvik, RP Macdonagh, SPSS Inc, TB Ustun, WHOQoL Group, Willy de Weerdt, World Health Organisation, World Health Organisation, World Health Organization, X Badia   +38 more
core   +6 more sources

Cost‐effectiveness of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: economic evaluation alongside the STent Or NEphrostomy (STONE) randomised controlled trial

BJU International, EarlyView.
Objective To evaluate whether percutaneous nephrostomy (PCN) is cost‐effective compared to JJ ureteric stent in the acute treatment of obstructive urolithiasis. Patients and Methods A randomised controlled non‐inferiority trial with 204 patients with obstructive urolithiasis requiring decompression.
Hugo W. Schuil, Nora Hendriks, Mohamed El Alili, Judith E. Bosmans, Ruben G. Duijnhoven, Bart C.H. Oskam, Tom J.H. Arends, Diederick Duijvesz, Alexander D. Horsch, Bart van der Heij, Irene Tjiam, Hans van Overhage, Armand B.G.N. Lamers, Otto M. van Delden, Wout Scheepens, Jamie M.A. Drossaerts, Frank C.H. d'Ancona, Steven Boering, Janneke I.M. van Uhm, Rutger W. van der Meer, Herman J.H. van Roijen, Martin de Kiefte, Ad J.M. Hendrix, Saskia Weltings, Rob C.M. Pelger, Harrie P. Beerlage, Guido M. Kamphuis, Barbara M.A. Schout   +27 more
wiley   +1 more source

Preparatory study for the revaluation of the EQ-5D tariff: methodology report. [PDF]

, 2014
BACKGROUND: EQ-5D is a widely used generic measure of health with a 'tariff', or preference weights, obtained from the general population, using time trade-off (TTO).
Bansback, Nick, Brazier, John, Buckingham, Ken, Cairns, John, Devlin, Nancy, Dolan, Paul, Hole, Arne Risa, Kavetsos, Georgios, Longworth, Louise, Mulhern, Brendan, Rowen, Donna, Tsuchiya, Aki   +11 more
core   +3 more sources

Patient‐reported outcome measures of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: results of the STent Or NEphrostomy (STONE) randomised controlled trial

BJU International, EarlyView.
Objective To compare the effects of percutaneous nephrostomy (PCN) and JJ ureteric stent (JJ) for urinary tract decompression in patients with obstructive urolithiasis on health‐related quality of life (HRQoL), pain scores, urinary symptoms, and patient satisfaction.
Hugo W. Schuil, Nora Hendriks, Ruben G. Duijnhoven, Bart C. H. Oskam, Tom J. H. Arends, Diederick Duijvesz, Alexander D. Horsch, Bart van der Heij, Irene M. Tjiam, Hans van Overhagen, Armand B. G. N. Lamers, Otto M. van Delden, Wout A. Scheepens, Jamie M. A. Drossaerts, Frank C. H. d'Ancona, Steven Boering, Janneke I. M. van Uhm, Rutger W. van der Meer, J. Herman van Roijen, Martin de Kiefte, Ad J.M. Hendrikx, Saskia Weltings, Rob C. M. Pelger, Harrie P. Beerlage, Barbara M. A. Schout, Guido M. Kamphuis   +25 more
wiley   +1 more source