Results 41 to 50 of about 47,291 (279)
Geriatrics, Gerontology and AgingObjective: To map the dimensions of quality of life in patients with heart failure (HF) and sarcopenia. Methods: The scoping review will adhere to the JBI Manual for Evidence Synthesis methodology and will be reported following the Preferred Reporting ...
Valéria Gonçalves da Silva +4 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park +19 more
wiley +1 more source
Quality of Life in Autism: A Systematic Review and Meta‐Analysis of Patients and Caregivers
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition associated with significant challenges in daily functioning and well‐being. Caregivers often experience substantial psychological and physical burden. However, comprehensive synthesis of quality of life (QoL) outcomes for both individuals with ASD and their caregivers ...
Kamila Castro +11 more
wiley +1 more source
Translational development of crisugabalin for neuropathic pain
British Journal of Clinical Pharmacology, EarlyView.Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João +5 more
wiley +1 more source
, 2006 Objective. The aim of this study is to propose a new approach for modelling the EQ-5D VAS, in order to explain the lifestyle determinants effect using the quantile regression analysis. Methods and Results.
BROCCOLI, SERENA +3 more
core +1 more source
Sanamed, 2017 Objectives: This study aimed to investigate the relationship between physical activitylevel and health related quality of life in elderly people. Design: Between January and April 2017, a cross-sectional study of 114 elderly people (73 males and 41 ...
Walid Kamal M. Abdelbasset +1 more
doaj +1 more source
Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset
Clinical Pharmacology &Therapeutics, EarlyView.Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit +6 more
wiley +1 more source
Health and Quality of Life Outcomes, 2021 Background With the increase of the number of smokers, tobacco exposure among pregnant women is becoming more and more common. Pregnant women exposed to first-hand smoke and second-hand smoke are susceptible to physiological and psychological health ...
Weiwei Sun +11 more
doaj +1 more source
Ethnic differences in health related quality of life for patients with type 2 diabetes [PDF]
, 2014 Background: The objective of this study was to investigate the association between ethnicity and health related quality of life (HRQoL) in patients with type 2 diabetes. Methods: The EuroQol EQ-5D measure was administered to 1,978 patients with type 2
Stavros Petrou +12 more
core +1 more source
EuroQoL in assessment of the effect of pulmonary rehabilitation COPD patients [PDF]
Respiratory Medicine, 2008 The effect of pulmonary rehabilitation on EuroQol in COPD patients has not been investigated previously.Two hundred and twenty nine consecutive COPD patients who had completed a 7-week pulmonary rehabilitation programme were assessed with EuroQol five-dimension questionnaire (EQ-5D), endurance shuttle walk test (ESWT), and the St George's Respiratory ...
Ringbaek, Thomas +3 more
openaire +3 more sources