Results 41 to 50 of about 69,559 (248)

Analysing randomised controlled trials with missing data : Choice of approach affects conclusions [PDF]

open access: yes, 2012
Copyright © 2012 Elsevier Inc. All rights reserved.
Fayers, Peter   +2 more
core   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Comparison of Paresthesia Mapping With Anatomic Placement in Burst Spinal Cord Stimulation: Long‐Term Results of the Prospective, Multicenter, Randomized, Double‐Blind, Crossover CRISP Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Spinal cord stimulation (SCS) is an effective therapy for chronic intractable pain. Conventional SCS involves electrode placement based on intraoperative paresthesia mapping; however, newer paradigms like burst may allow for anatomic placement of leads.
Adnan Al‐Kaisy   +13 more
wiley   +1 more source

Toward a validated European instrument to measure the socioeconomic impact of cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The Financial Index of Toxicity (FIT) evaluates patients' experiences of financial strain after cancer diagnosis. Originally developed in Canada for head and neck cancer patients, the applicability of FIT to other populations remains uncertain. This study assessed the validity of FIT in Europe using patient‐level data from six countries and
Jasper Ubels   +6 more
wiley   +1 more source

A Randomized, Sham‐Controlled Trial of Repetitive Transcranial Magnetic Stimulation Targeting M1 and S2 in Central Poststroke Pain: A Pilot Trial

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Central poststroke pain (CPSP), a neuropathic pain condition, is difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) targeted to the primary motor cortex (M1) can alleviate the condition, but not all patients respond. We aimed to assess a promising alternative rTMS target, the secondary somatosensory cortex (S2),
Juhani Ojala   +10 more
wiley   +1 more source

RELATIONSHIP BETWEEN PHYSICAL ACTIVITY AND HEALTH-RELATED QUALITY OF LIFE IN ELDERLY PEOPLE: A CROSS SECTION STUDY

open access: yesSanamed, 2017
Objectives: This study aimed to investigate the relationship between physical activitylevel and health related quality of life in elderly people. Design: Between January and April 2017, a cross-sectional study of 114 elderly people (73 males and 41 ...
Walid Kamal M. Abdelbasset   +1 more
doaj   +1 more source

Evaluation of the effectiveness and cost-effectiveness of Families for Health V2 for the treatment of childhood obesity : study protocol for a randomized controlled trial [PDF]

open access: yes, 2013
Background: Effective programs to help children manage their weight are required. Families for Health focuses on a parenting approach, designed to help parents develop their parenting skills to support lifestyle change within the family.
Griffiths, Frances   +13 more
core   +3 more sources

The Burden of Disease of Treatment‐Seeking Patients With a Cluster‐C Personality Disorder in the Netherlands; Quality of Life, Functioning, and Societal Costs

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Cluster‐C personality disorders (PDs) are common in the general population but often overlooked in scientific research and clinical practice. An important step to increase awareness for timely diagnosis and treatment of cluster‐C PDs is to investigate the burden of disease in terms of quality of life (QoL), daily functioning and the associated
Iuno Z. Groot   +5 more
wiley   +1 more source

Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Low back pain is the leading cause of disability worldwide and one of the most common reasons for seeking healthcare. Despite numerous care strategies, patients with low back pain continue to exhibit poor outcomes. Spinal cord stimulation (SCS) is an evidence‐based therapeutic modality for patients with failed back surgery syndrome ...
Jan M. Eckermann   +5 more
wiley   +1 more source

Maternal tobacco exposure and health-related quality of life during pregnancy: a national-based study of pregnant women in China

open access: yesHealth and Quality of Life Outcomes, 2021
Background With the increase of the number of smokers, tobacco exposure among pregnant women is becoming more and more common. Pregnant women exposed to first-hand smoke and second-hand smoke are susceptible to physiological and psychological health ...
Weiwei Sun   +11 more
doaj   +1 more source

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