Results 121 to 130 of about 3,468 (199)
Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)
JOR SPINE, Volume 9, Issue 3, September 2026.From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai +5 morewiley +1 more sourceUK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder
Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.A case series studying outcomes up to 18 months in autistic patients from the UK Medical Cannabis Registry. ABSTRACT Introduction
Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with distressed behaviors and psychological challenges.Arushika Aggarwal, Simon Erridge, Madhur Varadpande, Evonne Clarke, Katy McLachlan, Ross Coomber, Muhammed Asghar, Urmila Bhoskar, Matthieu Crews, Andrea De Angelis, Muhammad Imran, Fariha Kamal, Laura Korb, Gracia Mwimba, Simmi Sachdeva‐Mohan, Gabriel Shaya, James J. Rucker, Mikael H. Sodergren +17 morewiley +1 more sourceCharacterising the Economic Burden of Functional Dyspepsia: A Cost‐of‐Illness Study of Direct and Indirect Costs
United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.ABSTRACT Background
Functional dyspepsia (FD) is a prevalent disorder of gut‐brain interaction (DGBI) and is associated with substantial impact on health care utilisation. However, analyses examining patient‐specific characteristics that contribute to this burden remain limited.Daan H. C. A. Bosch, Brigitte A. B. Essers, Abraham B. Beckers, Johanna T. W. Snijkers, Bjorn Winkens, Ad A. M. Masclee, Daniel Keszthelyi +6 morewiley +1 more sourceImpaired Pre‐Critical Illness Quality of Life in Elderly ICU Patients
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.ABSTRACT Background
The EuroQol EQ‐5D‐5L is recommended to assess health‐related quality of life (HRQoL) in intensive care unit (ICU) survivors and included in many national ICU registries at the time of follow‐up. While establishing baseline HRQoL in elderly ICU survivors is important for informing follow‐up services, it is rarely performed in ...Shirin K. Frisvold, Bjørn A. Kroken, Daniel Bergum, Kristin Sandal‐Berg, Ole K. Fossum, Pål Klepstad, Reidar Kvåle, Hans Flaatten, Andrew M. Garratt +8 morewiley +1 more sourceBlood Pressure Targets During General Anaesthesia in High‐Risk Patients—A Randomised Clinical Feasibility Trial
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.ABSTRACT Background
There is limited high‐quality evidence to guide haemodynamic and respiratory management during general anaesthesia. The goal of this trial was to test the feasibility of testing different ventilatory settings and blood pressure targets.Maria B. Pælestik, Benjamin H. Risager, Signe Ø. Mortensen, Olav L. Schjørring, Jannie Bisgaard, Kasper G. Berthelsen, Rikke Balsløv, Leif Bach, Kim B. Pælestik, Jørgen G. R. Rossau, Carsten Poulsen, Christoffer Sølling, Jannie T. Sørensen, Mathilde Enevoldsen, Lærke D. D. Petersen, Stine T. Zwisler, Nicole M. Brahe, Anders M. Rasmussen, Ida A. Guldberg, Maria A. Joost, Henning Bay Nielsen, Ulrick S. Espelund, Lone Dragnes Brix, Jens A. K. Petersen, Christian F. Eriksen, Anders G. Kjærgaard, Pia D. Dinesen, Malene L. Abildgren, Mikael F. Vallentin, Marie K. Jessen, Simon T. Vistisen, Casper H. Nørholt, Cecilie D. Baltsen, Lotte K. Andersen, Frederik G. Hansen, Lea W. Frilund, Sofie Winther, Asger Granfelt, Lars W. Andersen +38 morewiley +1 more sourcePatient‐reported outcomes for monitoring substance use treatment: A systematic review of single‐item measures
Addiction, Volume 121, Issue 9, Page 2292-2316, September 2026.Abstract Background and aims
Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (Thomas J. Reese, Hilary A. Tindle, Justin Bachmann, Adam Wright, Jessica S. Ancker, Carolyn M. Audet, Mauli V. Shah, Bryan D. Steitz, Michael H. Levin, Kristopher A. Kast, David Marcovitz, Amanda von Horn, A. Taylor Kelley, John F. P. Bridges +13 morewiley +1 more sourceThe feasibility of mindfulness‐based relapse prevention for adults with substance use disorders (illicit drugs) in a Chinese population: A pilot randomized controlled trial
Addiction, Volume 121, Issue 9, Page 2433-2449, September 2026.Abstract Background and aims
Mindfulness‐based relapse prevention (MBRP) has been shown to be beneficial to individuals with substance use disorder (SUD) in the West. The current pilot study aimed at testing the feasibility of MBRP in a Chinese population.Ka Tsun Ting, Ivan Chun Him Leung, Dicken Cheong Chun Chan, Ken On Tai Yu, Wai Kwong Tang, Fu Chan, Alan Ka Lam Tang, Helen Shuk Wah Ma, Benjamin Hon Kei Yip, Daisy Dexing Zhang, Sarah Bowen, Samuel Yeung Shan Wong +11 morewiley +1 more sourceThe Burden of Small Fiber Neuropathy: Changes in Pain, Costs, and Quality of Life Before and After Diagnosis
Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.ABSTRACT Background and Aims
Small fiber neuropathy (SFN) is a peripheral neuropathy causing neuropathic pain, reduced quality of life (QoL), and high societal costs. Previous studies assessed these societal costs before a definitive diagnosis was established, leaving it unclear whether diagnostic confirmation affects costs, pain intensity, or QoL ...Dennis Kool, Margot Geerts, Lloyd Brandts, Merel Kimman, Caroline M. L. Gorissen‐Brouwers, Catharina G. Faber, Ingemar S. J. Merkies, Janneke G. J. Hoeijmakers +7 morewiley +1 more sourceDeveloping a Set of Core Patient‐Reported Outcomes for Kidney Replacement Therapy: A Modified Delphi Study
Journal of Renal Care, Volume 52, Issue 3, September 2026.ABSTRACT Background
Patient‐reported outcome measures can highlight the impact of kidney failure and kidney replacement therapy on a person's health‐related quality of life and symptom burden. But their implementation is limited and heterogeneous within Australian and New Zealand kidney care.Jessica Nikolovski, Brendan Smyth, Shyamsundar Muthuramalingam, Stephen McDonald, Jessica Roydhouse, Olalekan Lee Aiyegbusi, Claudia Rutherford, Amy Luchterhand, Paolo Cardelli, Rachael L. Morton, the ANZDATA PROMs Delphi Group +10 morewiley +1 more source