Results 71 to 80 of about 11,388 (196)

Comparative Study of Tympanic Membrane Regeneration Therapy for Chronic Otitis Media

The Laryngoscope, Volume 136, Issue 9, Page 4006-4014, September 2026.
This study compared tympanic membrane regeneration therapy (TMRT) with conventional tympanoplasty (CTP) for the treatment of chronic suppurative perforated otitis media (COM). TMRT has many advantages over CTP as a surgical treatment for COM. In particular, significant differences were observed in operative time, hearing improvement, and patient ...
Shin‐ichi Kanemaru, Rie Kanai, Tomoya Yamaguchi, Shin‐ichiro Kita, Ryohei Yuki, Masayuki Kitano, Razumu Shirai, Hiroyuki Harada, Toshiki Maetani   +8 more
wiley   +1 more source

Functional Anatomy of the Eustachian Tube

International Journal of Immunopathology and Pharmacology, 2010
The Eustachian tube (ET) is divided in 3 portions: a bony portion, a cartilaginous portion, and a junctional portion. From an anatomical-functional point of view, the bony portion of ET is the region of ventilation and clearance of secretions, and is lined by pseudostratified, ciliated, columnar epithelium, with an anti-gravitational direction of the ...
Cunsolo, E, Marchioni, D, Leo, G, Incorvaia, C, Presutti, L   +4 more
openaire   +5 more sources

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Treatment of middle ear ventilation disorders: sheep as animal model for stenting the human Eustachian tube--a cadaver study.

PLoS ONE, 2014
Eustachian tube disorders can lead to chronic otitis media with consecutive conductive hearing loss. To improve treatment and to develop new types of implants such as stents, an adequate experimental animal model is required.
Felicitas Miller, Alice Burghard, Rolf Salcher, Verena Scheper, Wolfgang Leibold, Thomas Lenarz, Gerrit Paasche   +6 more
doaj   +1 more source

A Biomimetic Starfish‐Inspired Magnetic Soft Robot with Ultrasound Monitoring for Targeted Inflammatory Bowel Disease Therapy

Advanced Sensor Research, Volume 5, Issue 8, August 2026.
This work introduces a starfish‐inspired magnetic soft robot for localized, long‐term inflammatory bowel disease therapy. Featuring biomimetic multi‐arm microspines and magnetic actuation, it navigates the gastrointestinal tract, adheres firmly, and releases drugs on demand, monitored by ultrasound, with validated biosafety and ex vivo therapeutic ...
Ziheng Xu, Ruomeng Xu, Ieng Ieng Leong, Zehao Wu, Qingsong Xu   +4 more
wiley   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1783-1798, August 2026.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source

What do we know about the diagnosis and treatment of Eustachian tube dysfunction?

Postępy w Chirurgii Głowy i Szyi
The Eustachian tube performs a ventilatory and drainage function for the middle ear. Its dysfunction can lead to various pathologies, such as inflammations, cholesteatoma formation, hearing loss, and, in severe cases, otogenic complications.
Marta Janura, Piotr Dąbrowski
doaj   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, Volume 48, Issue 8, Page 2271-2280, August 2026.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source

Phenotypic Subtypes of Obstructive Eustachian Tube Dysfunction as Defined by Cluster Analysis

The Laryngoscope, Volume 136, Issue 8, Page 3416-3424, August 2026.
Obstructive ETD encompasses five clinically distinct phenotypes, ranging from mild, post‐upper respiratory infection presentations to chronic, bilateral disease driven by sinusitis and reflux. These were identified through hierarchical cluster analysis of 490 patients using seven key clinical variables.
Jenilkumar H. Patel, Duncan G. J. Green, Manal S. Malik, Steven X. Wang, Edward D. McCoul   +4 more
wiley   +1 more source

Sinonasal Inflammatory Burden on Computed Tomography in Adults With Obstructive Eustachian Tube Dysfunction: A Case–Control Study

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) and Eustachian tube dysfunction (ETD) frequently coexist, yet objective data quantifying their relationship remain scarce. Because both conditions can reflect shared mucosal inflammation, we investigated whether adults with objectively verified ETD harbor a larger paranasal sinus inflammatory burden on
Dachan Kim, Jeong Gum Lee, Seong Hoon Bae   +2 more
wiley   +1 more source