Synthesis of Celecoxib-Eutectic Mixture Particles via Supercritical CO2 Process and Celecoxib Immediate Release Tablet Formulation by Quality by Design Approach [PDF]
Significant improvements in the wettability and dissolution rate of celecoxib (CEL), a poorly soluble selective cyclooxygenase-2 (COX-2) inhibitor, have been shown by Huyn et al., 2019 by combining the binary pharmaceutical compositions including CEL and
Seung-Hyeon Hong +4 more
doaj +2 more sources
Zn-based eutectic mixture as anolyte for hybrid redox flow batteries. [PDF]
Developing greener batteries with new chemistries is a formidable challenge, and a major focus for years to come. Redox flow batteries are receiving increasing research interest for grid-scale electrochemical energy storage owing to their unique ...
Wang Y +7 more
europepmc +2 more sources
An expeditious and environmentally benign synthesis of dispiro-3-phenylpyrrolothiazoles in ACI/EG eutectic mixture and its antioxidant and antimicrobial activities against urinary tract pathogens [PDF]
The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phenylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally supported solvents and to evaluate their ...
Govindasami Periyasami +8 more
doaj +2 more sources
Lipase‐Catalysed Polymerization of Eutectic Mixtures
AbstractAiming to reduce the toxicity and operational costs often associated to chemical processes, the enzymatic synthesis is applied herein as a sustainable route for producing polyesters. The use of NADES’ (Natural Deep Eutectic Solvents) components as a source of monomers for the synthesis of polymers through lipase‐catalyzed esterification in an ...
David S. Freitas +6 more
openaire +3 more sources
Eutectic Formation of Naproxen with Some Dicarboxylic Acids
Eutectic formation with additives is one of the established methods to improve the dissolution behaviors of active pharmaceutic ingredients (APIs). The improvement is mainly due to the increase in the surface area for dissolution, which originates from ...
Dahye Kim, Soeun Jang, Il Won Kim
doaj +1 more source
Deep eutectic solvents have quickly attracted the attention of researchers because they better meet the requirements of green chemistry and thus have the potential to replace conventional hazardous organic solvents in some areas. To better understand the nature of these mixtures, as well as expand the possibilities of their use in different industries,
Andrey Shishov +3 more
openaire +2 more sources
Medazepam, citric acid and their binary mixtures were studied using differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) for thermal and structural properties. The DSC data show a simple eutectic peak at 370 K.
Cristina Macasoi +2 more
doaj +1 more source
Thermophysical properties of austenitic stainless steel containing boron carbide in a solid state
In a core disruptive accident scenario, boron carbide, which is used as a control rod material, may melt below the melting temperature of stainless steel owing to the eutectic reaction with them.
Toshihide TAKAI +2 more
doaj +1 more source
Insights into the Nature of Eutectic and Deep Eutectic Mixtures [PDF]
A stricter definition of a deep eutectic solvent (DES) is urgent, so that it may become a sound basis for further developments in this field. This communication aims at contributing to deepening the understanding of eutectic and deep eutectic mixtures concerning their definition, thermodynamic nature and modelling.
Martins, Mónia A.R. +2 more
openaire +2 more sources
Depicting polymorphism in eutectic mixtures
Abstract Objective The present investigation unveils the existence of polymorphism in eutectic mixtures of linezolid with syringic acid, fumaric acid and isonicotinamide. This is a first of its kind study confirming polymorphism in binary mixtures.
Pawanpreet Singh, Renu Chadha
openaire +1 more source

