Results 21 to 30 of about 2,920 (181)
Attitude of doctors toward euthanasia in Delhi, India
Introduction: Deliberation over euthanasia has been enduring for an extended period of time. On one end, there are populaces talking for the sacrosanctity of life and on the other end, there are those, who promote individual independence.
Sheetal Singh +4 more
doaj +1 more source
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan +29 more
wiley +1 more source
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li +9 more
wiley +1 more source
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto +12 more
wiley +1 more source
New Generation of Human Rights: Somatic Rights
Scientific and technological progress, especially in the area of medicine, genetics, biology and chemistry gives a lot of possibilities and raises a lot problem to us.
A. A. Abashidze, A. M. Solntsev
doaj +1 more source
Emotional responses of veterinary students to first encounters with animal body donors
Abstract Students' first encounters with animal body donors in higher education are a formative and also potentially stressful experience. The complex emotions elicited by body donor use in learning and their effects on professional development have been documented in medical students, but are far less explored in veterinary medical counterparts.
S. Regnault, C. Basu, S. Channon
wiley +1 more source
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan +8 more
wiley +1 more source
Voluntary Active Euthanasia: The Debate [PDF]
Voluntary active euthanasia refers to a clearly competent patient making a voluntary and persistent request for aid in dying (Brock 1999; Ogubanjo & Knapp van Bogaert 2008). In this case, the individual or a person acting on that individual’s behalf (physician or lay person, depending on the law of the country) takes active steps to hasten death ...
openaire +1 more source
Impact of evidence‐based information on horse owners' misconceptions of colic
Abstract Background Misconceptions can be defined as ‘false, persistent beliefs’ or ‘inaccurate, prior knowledge’ and can influence decision‐making. Objectives To investigate the impact of evidence‐based information on UK horse owners' decision‐making for colic. Study Design Mixed‐methods cross‐sectional study.
K. L. Burrell +3 more
wiley +1 more source
ABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Zhen Huang +9 more
wiley +1 more source

