Results 81 to 90 of about 18,319 (240)

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

International Journal of Eating Disorders, Volume 59, Issue 1, Page 54-69, January 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai, Nanami Wada, Shinji Sakamoto, Kenji Miyazaki, Taro Kato, Yoshihiro Horiuchi, Hiroshi Kirii, Hoang Duy Nguyen, Kenji Hinotsu, Yoshio Ohya, Takahiro Asada, Akiyoshi Yokode, Yuko Okahisa, Haruko Miyazaki, Toshitaka Oohashi, Manabu Takaki   +15 more
wiley   +1 more source

Efficacy of Cordyceps militaris Polysaccharides in Ameliorating Alcoholic Liver Injury and Modulating Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
Our results suggest that Cordyceps militaris polysaccharide (CMP) can prevent alcohol‐induced oxidative stress and intestinal microbiota disorder, which may be related to the intestinal microbiota‐oxidative stress‐liver axis. ABSTRACT Alcoholic liver disease (ALD) is an inflammatory liver disorder caused by factors such as chronic excessive alcohol ...
Shi‐Rui Lu, Yu Huang, Shu‐Hang Li, Zi‐Xin Wang, Nuo‐Yan Wang, Qingyu Guo, Hong‐Jie Piao, Wenxiu Ji, Wei‐Wei Dong   +8 more
wiley   +1 more source

Maternal exercise is associated with a shift in adiposity distribution and improved markers of adipose health in offspring in mice

Pregnancy, Volume 2, Issue 1, January 2026.
Abstract Introduction Sedentary (SED) behavior is highly prevalent during pregnancy and is linked to negative maternal and fetal metabolic outcomes, even independent of weight gain and obesity. While emerging evidence suggests that increased maternal physical activity can counteract the detrimental effects of maternal SED behavior on offspring ...
Danielle Prentice, Sarah S. Bingaman, Serdar Ural, Pooja Menon, Yuval Silberman, Kirsteen N. Browning, Amy C. Arnold   +6 more
wiley   +1 more source

Astrocytic responses to binge ethanol in male and female mice: An examination of astrocytic glutamate transporters and density changes in the dorsal hippocampus

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The current work tested the hypothesis that sex differences in alcohol's effects are mediated by astrocytes. Using immunohistochemistry, qRT‐PCR, and ELISAs, we found that nondependent, binge‐like alcohol‐induced increases in hippocampal astrocyte density were more robust in females.
Candace Swepson, DaQuan R. Mebane, Diego Correia, Esohe H. Imafidon, Christopher P. Trevisani, James Nelson, S. Alex Marshall   +6 more
wiley   +1 more source

CO2 Reactivity but Not CO2‐Induced Orexin/c‐Fos Colocalization Differentially Predicts Alcohol‐Seeking Behaviour After Extinction and Retrieval‐Extinction in Rats

Addiction Biology, Volume 31, Issue 1, January 2026.
CO2 reactivity differentially predicted alcohol‐seeking behaviour in alcohol dependent and non‐dependent male and female rats after extinction and retrieval‐extinction. However, there were no relationships between orexin/c‐Fos colocalization and CO2 reactivity or return of alcohol‐seeking behaviour.
Marissa Raskin, Marcelle Olvera, Kylee A. Smith, Roberto Cofresí, Jason Shumake, Michael J. Telch, Michael W. Otto, Jasper A. J. Smits, Rueben Gonzales, Hongjoo J. Lee, Marie‐H. Monfils   +10 more
wiley   +1 more source

Voluntary active euthanasia: Justifications and regulations

, 2020
Voluntary active euthanasia is the most controversial category ofeuthanasia, which itself causes a great amount of discussions. This thesis defendsthe position that voluntary active euthanasia should be considered morally andlegally permissible under certain circumstances in which it becomes the ?mostappropriate medical treatment?.
openaire   +1 more source

Should self‐administered voluntary assisted dying be supervised? A Queensland case

Medical Journal of Australia, Volume 222, Issue 8, Page 390-393, May 2025.
Eliana Close, Katrine Del Villar, Ben P White   +2 more
wiley   +1 more source

Evaluation of leptin treatment on maintenance of body weight loss in diet‐induced obese mice

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 401-416, January 2026.
Abstract Aims To evaluate the therapeutic potential of leptin treatment for weight loss maintenance preclinically, through a systematic evaluation of leptin efficacy (a) following a period of weight loss stability (as in published clinical studies), and (b) across a range of circulating leptin concentrations achieved through a variety of different ...
Danna M. Breen, Rocío M. Saavedra‐Peña, Stephanie Joaquim, Jimmy Kong, Ryan Reese, J. Brent Kuzmiski, John C. Stansfield, Rhys Jones, Kendra K. Bence, V. Margaret Jackson   +9 more
wiley   +1 more source

Persons, Agents, and the End-of-life Decisions [PDF]

, 2002
Extensive discussions about the nature and value of personhood, of metaphysical and normative aspects of becoming a person and ceasing to be one, having been conducted at the very center of the debates on abortion, therapeutic human cloning, embryo ...
Klampfer, Friderik
core  

Dysphagia in an equine referral hospital, 182 cases

Equine Veterinary Journal, Volume 58, Issue 1, Page 134-142, January 2026.
Abstract Background Dysphagia describes a clinical sign of pathologies of the oral cavity, pharynx, and oesophagus that carries potentially serious consequences for horses. Given the diversity of differential diagnoses that may cause dysphagia, an understanding of the prevalence of dysphagia in hospitalised patients, the distribution of aetiologies and
Kevin M. Connolly, Krista Estell
wiley   +1 more source