Results 141 to 150 of about 4,160,670 (345)
Advanced Science, EarlyView.The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du +21 more
wiley +1 more source
Imaging‐Guided Microscale Photothermal Stereolithography Bioprinting
Advanced Science, EarlyView.This work establishes imaging‐guided microscale photothermal stereolithography bioprinting, achieving microscale photothermal aqueous printing for the first time. Key innovations include novel imaging‐guided stereolithography, unique NIR‐II photothermal initiator, and new bioink with viscosity modifier.
Jingyu Sun +9 more
wiley +1 more source
JBMR Plus, Volume 7, Issue 1, January 2023., 2023 ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira +7 more
wiley +1 more source
The risks of using continuous deep palliative sedation within the context of euthanasia
SHS Web of Conferences, 2016 Although palliative care is one of the main arguments among the opponents of euthanasia, the individual medical activities implemented within it are not always evaluated unequivocally.
Polaks R.
doaj +1 more source
THE TERMINAL QUALITY OF LIFE AND PASSIVE OR ACTIVE EUTHANASIA
International Journal for Quality in Health Care, 1990 The problems presented by the different categories of dying people are briefly discussed from the point of view of terminal quality of life. Euthanasia is used in its broader meaning, including both passive and active aspects. Passive euthanasia (PE) is exercised by withholding advanced or basic life support measures, the commonest form being do not ...
openaire +3 more sources
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
Advanced Science, EarlyView.This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim +12 more
wiley +1 more source
Advanced Science, EarlyView.Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu +12 more
wiley +1 more source
Activation Ensembles for Deep Neural Networks [PDF]
arXiv, 2017 Many activation functions have been proposed in the past, but selecting an adequate one requires trial and error. We propose a new methodology of designing activation functions within a neural network at each layer. We call this technique an "activation ensemble" because it allows the use of multiple activation functions at each layer.
arxiv
Letter: Active and passive euthanasia. [PDF]
Journal of Medical Ethics, 1975 R G Twycross, A G Flew
openaire +3 more sources
Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity
Journal of Orthopaedic Research, Volume 41, Issue 2, Page 316-324, February 2023., 2023 Abstract Nerve growth factor (NGF) is a neurotrophin that has been implicated in pain signaling, apoptosis, inflammation and proliferation. The resultant effects depend on interaction with two different receptors; tyrosine kinase A (TrkA) and p75NTR. NGF increases in synovial fluid from osteoarthritic joints, and monoclonal antibody therapy is trialed ...
Anna Kendall +2 more
wiley +1 more source