Animal Models and Experimental Medicine, EarlyView.Tumor growth inhibition does not predict survival benefit in a clinically relevant metastasis model. Tumor local growth and systemic metastasis represent distinct biological processes. In the 4T1‐OtR model, although chemotherapy significantly suppresses primary tumor growth, it fails to prevent distant metastasis or extend overall survival.
Lingli Luo +6 more
wiley +1 more source
Methodologies to Identify Metabolic Pathway Differences Between Emaciated and Moderately Conditioned Horses: A Review of Multiple Gene Expression Techniques. [PDF]
Animals (Basel)Austin MMP +3 more
europepmc +1 more source
Challenges of modeling pristane‐induced lupus in non‐human primates
Animal Models and Experimental Medicine, EarlyView.Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Seeking consensus on dilemmas related to euthanasia in dementia based on an advance directive: a Delphi study from a medical, ethical and legal perspective. [PDF]
J Med Ethicsde Boer ME +6 more
europepmc +1 more source
Comparative Efficacy of High-Dose Daptomycin Monotherapy versus Combination Therapy for Daptomycin-Resistant <i>Enterococcus faecium</i> Endocarditis in a Rat Model. [PDF]
Infect Drug ResistYang CJ, Wang JT, Yang JL, Chuang YC.
europepmc +1 more source
Polylimonene Improves the In Vivo Wound Healing Performance of Sodium Alginate‐Based Hydrogels
Journal of Applied Polymer Science, EarlyView.An oligomer derived from orange peel essential oil incorporated into an alginate hydrogel was shown to be biocompatible and to exhibit a high capacity for in vivo incisional wound healing, as confirmed by experimental assays and mathematical models fitted to the data describing wound area reduction as a function of the dressing‐tissue contact time ...
Roniérik Pioli Vieira +5 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Fasting is a practice in the aquaculture industry that aims to reduce feed costs. This practice can affect the gastrointestinal system of fish. The intestine plays a pivotal role in the nutrition and overall health of fishes. The present study sought to evaluate the effects of fasting and refeeding on body weight, intestine somatic index (ISI),
Karine Nathiele Nogueira Farias +7 more
wiley +1 more source
End-of-life decisions and ethics on the big screen: reflecting narratives of 'a life fully lived'. [PDF]
Med Health Care PhilosWagensonner F, Sahm A, Frewer A.
europepmc +1 more source
The Anatomical Record, EarlyView.Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley +1 more source