Results 91 to 100 of about 20,723 (178)
Heart dysfunction in a rat model with autosomal recessive polycystic kidney disease
The Journal of Physiology, EarlyView.Abstract figure legend Our results demonstrate a diastolic dysfunction in animals with severe kidney disease. Moreover, chronic kidney disease (CKD)‐induced heart fibrosis and hypertrophy are associated with a dysregulation of cardiokine signalling in autosomal recessive polycystic kidney disease (ARPKD) animals. Created using BioRender.com.
Nathalie Gayrard +11 more
wiley +1 more source
Hemodynamics and Drinking in the Giraffe
Acta Physiologica, Volume 241, Issue 5, May 2025.ABSTRACT Background The circulation of 4–6 m tall giraffes is markedly affected by gravity. To ensure cerebral perfusion, upright giraffes generate a blood pressure in excess of 200 mmHg. Before drinking, the head is lowered by 3–5 m, providing exceptional hemodynamic challenges.
Christian Aalkjær +17 more
wiley +1 more source
On Networks with Active and Passive Agents [PDF]
arXiv, 2014 We introduce an active-passive networked multiagent system framework, which consists of agents subject to exogenous inputs (active agents) and agents without any inputs (passive agents), and analyze its convergence using Lyapunov stability.
arxiv
Nicorandil treatment improves survival and spatial learning in aged granulin knockout mice
Brain Pathology, Volume 35, Issue 3, May 2025.Progranulin knockout mice display a profound reduction in survival, as well as increased inflammation and cognitive impairment. Treatment of these mice with nicorandil—a K+ATP channel agonist, decreased mortality and improves cognitive impairment. Abstract Mutations in the human granulin (GRN) gene are associated with multiple diseases, including ...
Dana M. Niedowicz +11 more
wiley +1 more source
Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.ABSTRACT Background Approximately 50%–60% of paraplegic deep pain negative (DPN) dogs secondary to thoracolumbar intervertebral disc extrusion (TL‐IVDE) recover ambulation after surgery. Mean F‐wave duration has been associated with injury severity in TL‐IVDE in dogs, but the relationship to outcome is unknown. Objective Evaluate the prognostic utility
Go Togawa +4 more
wiley +1 more source
New experimental model of exposure to environmental tobacco smoke [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To describe a new model to passive smoking for rodents. METHODS: Twenty rats were distributed into two study groups (N=10): control group (CG), that was not exposed to tobacco smoke and used as normal standard for biochemical and histological ...
Marcus Vinicius Henriques Brito +6 more
doaj
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
Are Passive Spiral Galaxies truly 'passive' and 'spiral'?: a Near-Infrared perspective [PDF]
arXiv, 2005 Passive spiral galaxies - unusual galaxies with spiral morphologies but without any sign of on-going star formation - have recently been shown to exist preferentially in cluster infalling regions. This discovery directly connects passive spiral galaxies to cluster galaxy evolution studies, such as the Butcher-Oemler effect or the morphology-density ...
arxiv
Dr. Peter Emil Becker and the Third Reich: Correspondence
American Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.ABSTRACT Peter Emil Becker was a German neurologist who is remembered for his studies of muscular dystrophies. Becker muscular dystrophy and Becker myotonia are named after him. His biography appeared in the American Journal of Medical Genetics in 1985.
Tilman Becker
wiley +1 more source
Cold‐induced fibrosis and metabolic remodeling in the turtle (Trachemys scripta) ventricle
Acta Physiologica, Volume 241, Issue 4, April 2025.Abstract Aim Cardiac fibrosis contributes to systolic and diastolic dysfunction and can disrupt electrical pathways in the heart. There are currently no therapies that prevent or reverse fibrosis in human cardiac disease. However, animals like freshwater turtles undergo seasonal remodeling of their hearts, demonstrating the plasticity of fibrotic ...
Adam N. Keen +11 more
wiley +1 more source