Results 141 to 150 of about 210,115 (312)
Epilepsia Open, EarlyView., 2022 Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou +7 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo +10 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding +16 more
wiley +1 more source
Attitudes of Michigan Physicians and the Public toward Legalizing Physician-Assisted Suicide and Voluntary Euthanasia [PDF]
, 1996 Jerald G. Bachman +5 more
openalex +1 more source
Cancer Patients Who Elect Euthanasia as an Option: An Argumentative Essay
Middle East Journal of Cancer, 2018 Euthanasia has initiated a debate in many countries on whether ending a patient's life intentionally who suffers from a terminal stage cancer should be lawful or not. This topic has recently gained much attention.
Mahmoud Khaled Al Hamarsheh +1 more
doaj
Advanced Science, EarlyView.The present study reveals that PLAUR+ neutrophils are enriched in immunotherapy non‐responders and correlate with poor prognosis. PLAUR+ neutrophils dictate immunotherapy resistance in hepatocellular carcinoma by forming an immunosuppressive tumor microenvironment characterized by CD8+ T cell exclusion and macrophage‐dependent immune suppression.
Shaoqing Liu +11 more
wiley +1 more source
Towards the right to be killed?: Treatment refusal, assisted suicide and euthanasia in the United States and Canada [PDF]
, 1996 Trudo Lemmens
openalex +1 more source