Results 231 to 240 of about 255,405 (374)
Attitudes Toward Euthanasia for Patients Who Suffer From Physical or Mental Illness
Kfir Levin, G. Bradley, Amanda L. Duffy
semanticscholar +1 more source
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan +10 more
wiley +1 more source
Euthanasia in End-of-Life Care: Ethical Compassion or Dilemma? [PDF]
Aghakhani N, Ewalds-Kvist BM, Naseri S.
europepmc +1 more source
The Movement Toward Physician-Assisted Suicide: A Step in the Wrong Direction [PDF]
Norris, Patrick
core +1 more source
Incidence and Prevalence of Reported Euthanasia Cases in Belgium, 2002 to 2023 [PDF]
Jacques Wels, Natasia Hamarat
openalex +1 more source
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang +12 more
wiley +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source

