Results 231 to 240 of about 337,152 (297)

Microparticles Expressing IL-1β Are Linked to Neuroinflammation and Cognitive Decline After Carbon Monoxide Poisoning. [PDF]

Int J Mol Sci
Arya AK, Sethuraman K, Waddell J, Bhat AR, Imtiyaz Z, Walia D, Liang Y, Cha YS, Lee Y, Moayedi S, Sward D, Thom SR.   +11 more
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Carbon Dioxide Euthanasia Selectively Affects Physiology of Murine Retinal Cells, Implicating Carbonic Anhydrase-Expressing Cell Populations. [PDF]

Invest Ophthalmol Vis Sci
Ignatova I, Koskelainen A.
europepmc   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Case Report: Surgical management of mandibular oral histiocytic sarcoma in a ragdoll cat with favorable outcome. [PDF]

Front Vet Sci
Seung BJ, Cho J, Lee B, Chon J, Kim K.
europepmc   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

More Danish cattle correctly euthanized after information campaign

, 2011
Thomsen, Peter T., Dam Otten, Nina, Andreasen, Sine Norlander   +2 more
core   +1 more source

<i>In vitro</i> and <i>in vivo</i> activity of omadacycline against <i>Mycobacterium tuberculosis</i>. [PDF]

Front Microbiol
Khan S, Nguyen D, Nikolic D, Wan B, Hossain A, Qader M, Cho S, Franzblau SG, Shetye GS.   +8 more
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Euthanasia of a macaque with self-injurious behavior in a visual neuroscience laboratory. [PDF]

Anim Adv
Horton JC.
europepmc   +1 more source