Results 41 to 50 of about 337,152 (297)

Racing‐associated fatalities in Norwegian and Swedish harness racehorses: Incidence rates, risk factors, and principal postmortem findings

Journal of Veterinary Internal Medicine, 2022
Background There are no reports on the number of fatalities or causes of death in the Norwegian and Swedish harness racehorses. Objectives The incidence rates (IRs), risk factors, and postmortem findings in horses that died or were euthanized associated ...
Ingunn Risnes Hellings, Eystein Skjerve, Erika Karlstam, Mette Valheim, Carl Fredrik Ihler, Constanze Fintl   +5 more
doaj   +1 more source

Allocation of sheep per room and day post-challenge each animal was euthanized.

, 2018
Allocation of sheep per room and day post-challenge each animal was euthanized.
Peter A. Durr (830162), Nagendrakumar Singanallur (5409839), Soren Alexandersen (83944), Hilary Bittner (3533069), Wilna Vosloo (235543), Jacquelyn Horsington (392994), Charles Nfon (294754)   +6 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Strangles and infarctive purpura hemorrhagica in a horse

Brazilian Journal of Veterinary Pathology
History: A euthanized 23-year-old Quarter Horse gelding with an ~1-week history of fever (102.5°F), clear nasal discharge and lymphadenopathy was euthanized.
Carolina Matto, Carmina Migoni, Michelle Rubio, Akinyi Nyaoke, Eileen Henderson, Francisco A. Uzal, Javier Asin   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Clonal architecture of intestinal tumors from the distal small intestine and colon of 31 mosaic mice euthanized when moribund.

, 2016
Clonal architecture of intestinal tumors from the distal small intestine and colon of 31 mosaic mice euthanized when moribund.
Terrah J. Paul Olson (2503693), Mary Kay Washington (347986), Alyssa A. Leystra (400804), Joseph M. Szulczewski (2503696), Linda Clipson (400806), Michael A. Newton (204762), Kevin W. Eliceiri (140016), Richard B. Halberg (400809), Christopher D. Zahm (2503690), Dawn M. Albrecht (640466), Andrew T. Thliveris (781008), Kristina A. Matkowskyj (640467), Malisa Middlebrooks (2503699)   +12 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Influences on the Decision to Euthanize a Compromised Pig

Animals
The decision to euthanize a compromised pig can be challenging for pig farmers and veterinarians. To understand more about the challenges in Germany, a cross-sectional online survey was conducted. Based on a hybrid design, the responses of 39 veterinarians and 62 pig farmers were analyzed to generate a list of common clinical signs associated with the ...
Julia Stoffregen, Tristan Winkelmann, Bettina Schneider, Michel Fehrmann, Kathrin Gerdes, Moana Miller, Jennifer Reinmold, Isabel Hennig-Pauka, Nicole Kemper, Christin Kleinsorgen, Karl-Heinz Tölle, Lothar Kreienbrock, Michael Wendt, Elisabeth grosse Beilage   +13 more
openaire   +3 more sources

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source