Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
La presencia del pH vaginal normal descarta el diagnóstico de la vaginosis bacteriana?
Introdución: la Vaginosis Bacteriana (VB) es una infección vaginal caracterizada por una alteración del medio ambiente vaginal con disminución en el contenido vaginal de Lactobacillus spp. e incremento de microorganismos Anaerobios, Gardenella vaginalis,
Miguel Tilli +5 more
doaj
Environmental Sustainability of Project Schedule Management by Earned Value Analysis [PDF]
The innovative aspect of this study is the explicit incorporation of environmental sustainability metrics into conventional Earned Value Analysis (EVA) to facilitate schedule-driven decision-making in construction projects.
Kalyana Chakravarthy P.R. +8 more
doaj +1 more source
Estudo e análise da ferramenta gerencial Eva® [PDF]
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho tem por objetivo geral apresentar o EVA® (Valor Econômico Agregado) – uma ferramenta gerencial de cálculo de desempenho empresarial ...
Souza, Rafael Adalberto de
core
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Introdução: as infecções cervicovaginais (CV) possuem relevância devido a suas potenciais complicações, tanto em pacientes obstétricas quantoem ginecológicas.
Miguel Tilli +4 more
doaj
Pentatrichomonas hominis COINFECTION IN A PUPPY FROM A SLOVENIAN ANIMAL SHELTER
A 3-month-old dog originating from a Slovenian animal shelter presented with acute bloody, soft, foamy and malodorous diarrhoea. The clinical examination, haematology and serum biochemistry were unremarkable.
Maja Brložnik +5 more
doaj +1 more source
Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park +7 more
wiley +1 more source

