Results 311 to 320 of about 32,714,285 (374)

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

An emotion-oriented product evaluation model based on BP neural network and improved dempster-shafer theory. [PDF]

Sci Rep
Wang K, Li K, Jiang X, Chen C.
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Evaluation of Evaluation

Behaviormetrika, 1974
openaire   +1 more source

Competency-Based Evaluation Methodology Enhances Learning During Internship: A Pilot Study. [PDF]

Adv Med Educ Pract
Wang W, Zhao Y, Zheng G, Zhao X, Chen W.
europepmc   +1 more source

Key features of sustainable capacities for risk communication in health emergencies: analysis of Joint External Evaluation. [PDF]

J Glob Health
Takeda A, Seino K, Okuda H, Saito T, Tomio J.   +4 more
europepmc   +1 more source

Value-based large language model agent simulation for mutual evaluation of trust and interpersonal closeness. [PDF]

Sci Rep
Sakamoto Y, Uchida T, Ishiguro H.
europepmc   +1 more source

Promoting Responsible DeepSeek Deployment in Health Care: Scoping Review Comparing Grey and White Literature.

J Med Internet Res
Jiang W, Wang D, Zeng Y, Huang J, Xu C, Liu C.   +5 more
europepmc   +1 more source