Results 111 to 120 of about 24,118 (260)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Application of analytic hierarchy process(AHP)on determinant of weight of nursing director leadership evaluation index system

open access: yesHuli yanjiu, 2016
Objective:To determine the weight of each index based on the construction of nursing director leadship evaluation index system recently.Methods:AHP was used to establish the hierarchy of nursing directors leadership evaluation index,construct judgment ...
张绍果, 黄萍英, 杨辉, 高超
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Survivability evaluation of network information system based on the cloud model and analytic hierarchy process

open access: yesTongxin xuebao, 2014
Considering the problem of quantitative evaluation for qualitative survivability data and indexes of network information systems, the proposed method gives a multi-level survivability evaluation framework based on cloud model theory and AHP method.
Yan-hua LIU, Guo-long CHEN, Rui-fen WU
doaj   +2 more sources

机械系统概念设计方案评价方法研究

open access: yesJixie chuandong, 2008
The evaluation of conceptual design schemes of mechanical products is an essential problem in the process of its conceptual design.At the stage of conceptual design,whether a correct and objective evaluation can be made on these design schemes will ...
苗鸿宾, 刘钊
doaj  

Price hedonics: a critical review [PDF]

open access: yes
This paper was presented at the conference "Economic Statistics: New Needs for the Twenty-First Century," cosponsored by the Federal Reserve Bank of New York, the Conference on Research in Income and Wealth, and the National Association for Business ...
Charles R. Hulten
core  

Risk Evaluation of Environmental Monitoring Indexes for Deep Excavation

open access: yes, 2011
The risk evaluation of environmental monitoring indexes during deep excavation was systematically investigated and applied to a real project. The risk analysis was carried out based on the collected environmental monitoring data.
Jiao Zhang
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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