Results 61 to 70 of about 24,118 (260)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Construction of related indexes of core competency training of dental specialist nurses

open access: yesHuli yanjiu, 2022
ObjectiveTo construct index system of core competence,training methods,and assessment and evaluation of dental specialist nurses.MethodsIndex system of core competence,training methods,and assessment and evaluation of dental specialist nurses were ...
CEN Qiong, YU Juan, JI Yudi, LYU Yun
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

What Do Business Climate Indexes Teach Us About State Policy and Economic Growth? [PDF]

open access: yes
State business climate indexes capture state policies that might affect economic growth. State rankings in these indexes vary wildly, raising questions about what the indexes measure and which policies are important for growth.
Marisol Cuellar Mejia   +2 more
core  

Google Scholar : the new generation of citation indexes [PDF]

open access: yes, 2005
Google Scholar (http://scholar.google.com/) provides a new method of locating potentially relevant articles on a given subject by identifying subsequent articles that cite a previously published article.
Noruzi, Alireza
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Severity evaluation indexes

open access: yes, 2014
Severity Evaluation Indexes are very useful instruments for the assessment of a patient with nail psoriasis. Their role is essential in clinical trials, baseline consultation, therapeutic strategy, and consequent follow-up. Therefore, they should be objective, reproducible, and simple to perform.
Rigopoulos, D., Prevezas, C.
openaire   +3 more sources

Price Indexes for Medical Care Goods and Services: An Overview of Measurement Issues [PDF]

open access: yes
We review in considerable detail the conceptual and measurement issues that underlie construction of medical care price indexes in the U.S., particularly the medical care consumer price indexes (MCPIs) and medical-related producer price indexes (MPPIs ...
Zvi Griliches   +4 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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