Results 51 to 60 of about 2,159,261 (311)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Suitability evaluation of underground space development in coal mining cities in Henan province

open access: yes矿业科学学报, 2023
This study proposes to evaluate the suitability of underground space development and utilization in coal mining cities, with the aim to promote reasonable utilization of underground space left behind after the closure of coal mines and avoid resource ...
Shi Beining, Xiang Zhonglin
doaj   +1 more source

Application of Natural Resources Indicators to Agricultural Land Management in Slovenia [PDF]

open access: yes, 2006
Th e group of indicators to establish the impact of land management measures on natural resources in the agricultural landscapes in Slovenia is discussed and identifi ed.
Andreja Borec, Branko Kramberger
core   +2 more sources

An Integrated Impact Indicator (I3): A New Definition of "Impact" with Policy Relevance

open access: yes, 2012
Allocation of research funding, as well as promotion and tenure decisions, are increasingly made using indicators and impact factors drawn from citations to published work.
Leydesdorff, Loet, Wagner, Caroline S.
core   +1 more source

Sustainability Assessment of indicators for integrated water resources management [PDF]

open access: yes, 2017
The scientific community strongly recommends the adoption of indicators for the evaluation and monitoring of progress towards sustainable development. Furthermore, international organizations consider that indicators are powerful decision-making tools ...
Botero, V   +5 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

A Systemic Approach to Evaluating Fintech-Driven Competitiveness in Commercial Banks: Integrating Delphi and ANP Methods

open access: yesSystems
In the context of fintech’s transformative impact on banking, many commercial banks blindly adopt emerging technologies, resulting in systemic inefficiencies.
Xin Wang, Wenxiu Hu, Na Guan
doaj   +1 more source

Monitoring Soil Characteristics in Organic Farming: A Comparison of Field vs. Laboratory Methods [PDF]

open access: yes, 2007
Soil quality plays a key role in organic farming. In practice its evaluation is not so simple because there are many indicators that could be used.
Kouril, Milan, Sarapatka, Borivoj
core  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

The diagnostic model for food security assessment of the Russian Arctic

open access: yesπ-Economy, 2022
The article is devoted to the formation of the diagnostic model for food security assessment of the Russian Federation Arctic zone (AZRF). The topicality of the research is due to the necessity of modernization of the Russian Arctic food supply system in
Kovzunova Eugenia   +3 more
doaj   +1 more source

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