Results 191 to 200 of about 6,199,232 (247)

Lives saved accountability scorecard

Annals of Global Health, 2015
J. Dieleman, H. Wang, M. Birger, C. Graves, T. Templin, C. Murray   +5 more
doaj   +1 more source

External validation of the COLOFIT colorectal cancer risk prediction model in the Oxford-FIT dataset: the importance of population characteristics and clinically relevant evaluation metrics. [PDF]

BMC Med
Tamm A, Shine B, James T, Withers J, Salih H, Noble T, Várnai KA, East JE, Abel G, Hamilton W, Rees C, Morris EJA, Davies J, Nicholson BD.   +13 more
europepmc   +1 more source

LinSEM: Linearizing segmentation evaluation metrics for medical images. [PDF]

Med Image Anal, 2020
Li J, Udupa JK, Tong Y, Wang L, Torigian DA.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A systematic approach to produce robust, comparable and timely cost-effectiveness estimates for a set of interventions: proof of concept in two low-income countries

Annals of Global Health, 2015
T. Cravo Oliveira, E. Gakidou, T. Vos, H. Higashi, C. Murray   +4 more
doaj   +1 more source

Alternative Criteria to Address Major Flaws of Common Evaluation Metrics for Dose Distributions Through Characterization of Stereotactic Irradiation Plans for Brain Metastases Using the High-Definition Dynamic Radiosurgery Platform. [PDF]

Cureus
Ohtakara K, Suzuki K.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A survey on deep learning in medical image registration: New technologies, uncertainty, evaluation metrics, and beyond. [PDF]

Med Image Anal
Chen J, Liu Y, Wei S, Bian Z, Subramanian S, Carass A, Prince JL, Du Y.   +7 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source