Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Somalia's new community health strategy: Strengthening primary health care and health system resilience. [PDF]
Ali MA +5 more
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Community Participation and the Making of Brazil's National Oral Health Policy. [PDF]
Narvai PC, Peres MA.
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Augmenting patient safety surveillance in radiation oncology with large language model-based root cause analysis: A proof-of-concept study. [PDF]
Wang Y +5 more
europepmc +1 more source
Supporting Healthier, Sustainable and Equitable Food Environments: A Rapid Review of Australian Local Government Action. [PDF]
Vargas C +4 more
europepmc +1 more source
Sexual harassment protocols at the European universities: An overview of key components and recommendations for improvement. [PDF]
Berbegal-Bernabeu M +12 more
europepmc +1 more source
Visible AI assistant outputs in psychosocial risk management: an OHP/OHS-grounded benchmark for governance and responsible use. [PDF]
Çögenli MZ.
europepmc +1 more source

