Results 31 to 40 of about 51,324 (221)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Effects of Instrumentality and Personal Force on Deontological and Utilitarian Inclinations in Harm-Related Moral Dilemmas

open access: yesFrontiers in Psychology, 2020
Moral dilemmas often concern actions that involve causing harm to others in the attempt to prevent greater harm. But not all actions of this kind are equal in terms of their moral evaluation.
Jonas Ludwig   +4 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Application of preventive medicine resources in the health insurance system

open access: yesEinstein (São Paulo)
Objective To identify the financial resources and investments provided for preventive medicine programs by health insurance companies of all kinds.
Karla Regina Dias de Oliveira   +2 more
doaj   +1 more source

APPLICATION OF PERFORMANCE INDICATORS TO A UNIVERSITY HOSPITAL

open access: yesInternational Journal of Health Services Research and Policy, 2016
Assessment” is the process of objectively understanding the state or condition of a thing, by observation and measurement. Assessment of something means taking a measure of its effectiveness.
İsmail YILDIZ, Eylem Can ÖZDEMİR
doaj   +1 more source

Temporal trend of drought and aridity indices in semi-arid pernambucano to determine susceptibility to desertification

open access: yesRBRH, 2020
In semi-arid regions, the use of drought and aridity indices in order to establish diagnoses and prognoses that help in water resources management is crucial, above all, for the evaluation of long-term water availability, and monitoring hydrological ...
Fabianny Joanny Bezerra Cabral da Silva   +1 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Evaluation of the ZIG-ZAIDS game: an entertaining educational tool for HIV/Aids prevention

open access: yesCadernos de Saúde Pública, 1999
This article presents the evaluation process for the ZIG-ZAIDS game, investigating the material's applicability in formal and informal educational contexts, i.e., how the game has been used by health professionals, parents, and the target population (pre-
Schall Virgínia T.   +3 more
doaj  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

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