Results 91 to 100 of about 7,832,301 (298)
Energy systems are currently transforming into configurations with a significant share of renewable energies to reduce greenhouse gas (GHG) emissions.
Andrea Schreiber +6 more
doaj +1 more source
Faculty Members’ Viewpoints towards Teacher Evaluation Process in Isfahan University of Medical Science [PDF]
Introduction: There are limited studies regarding teacher evaluation process. The goal of this study was to determine faculty members’ viewpoints regarding teacher evaluation process and its relationship with their characteristics in Isfahan University ...
Mina Tootoonchi +3 more
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
An evaluation model of islamic learning education program in madrasah aliyah
The purpose of this study is: (1) to create the products as the evaluation model learning programs of Islamic education in madrasah aliyah, suitable, precise, and accurate, (2) to know how to test the suitability of the model to obtain the evaluation ...
Anidi Anidi
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Study Concerning the Measure of Using Accounting, Economical and Administrative Evaluation in Practice [PDF]
Through genesis, accounting has appeared from the necessity of knowing and managingpatrimonial elements of the entities and for this purpose, many methods and techniques have beendeveloping.
Dreghiciu Andreea Elena
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
This paper is a case study of an artifact design and evaluation process; it is a reflection on how right thinking about design methods may at times result in sub-optimal results.
Bernstein, Michael +3 more
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