Results 171 to 180 of about 7,832,301 (298)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Portfolio practices in the principal evaluation process: A qualitative case study. [PDF]

Heliyon
Alkaabi AM, Abdallah AK.
europepmc   +1 more source

A Framework to Ensure Patient Partners Have Equal and Contributing Voices Throughout the Research Program Evaluation Process. [PDF]

Can J Kidney Health Dis, 2020
Hillier DR, Tang M, Clark W, MacDonald C, Connolly C, Large C, King M, Singer J, Levin A, Manns B, Konvalinka A, Scholey J, Rosenblum ND.   +12 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

The Flow of Living Kidney Donor Candidates Through the Evaluation Process: A Single-Center Experience in Ontario, Canada. [PDF]

Can J Kidney Health Dis
Habbous S, Montesi B, Masse C, Weernink C, Sarma S, Begen MA, Lam NN, Dipchand C, Yohanna S, Connaughton DM, Barnieh L, Garg AX.   +11 more
europepmc   +1 more source

Emergency response to terrorist attacks: results of the federal-conducted evaluation process in Germany. [PDF]

Eur J Trauma Emerg Surg, 2020
Wurmb T, Franke A, Schorscher N, Kowalzik B, Helm M, Bohnen R, Helmerichs J, Grueneisen U, Cwojdzinski D, Jung G, Lücking G, Weber M.   +11 more
europepmc   +1 more source

Evaluating the process: CHAPS process evaluation overview and experiences: 2002 evaluation report [PDF]

, 2002
Branigan, P, Stewart, W, Wellings, K
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Hollow Fiber Microreactor Combined with Digital Twin to Optimize the Antimicrobial Evaluation Process. [PDF]

Micromachines (Basel)
Noda K, Kasama T, Shinohara M, Hamada M, Matsunaga YT, Takai M, Ishii Y, Miyake R.   +7 more
europepmc   +1 more source

Association of sociocultural factors with initiation of the kidney transplant evaluation process. [PDF]

Am J Transplant, 2020
Hamoda RE, McPherson LJ, Lipford K, Jacob Arriola K, Plantinga L, Gander JC, Hartmann E, Mulloy L, Zayas CF, Lee KN, Pastan SO, Patzer RE.   +11 more
europepmc   +1 more source