Results 141 to 150 of about 6,674,346 (214)

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Autologous platelet-rich plasma serum versus punctal plugs for treatment of moderate to severe dry eye disease

Journal of the Egyptian Ophthalmological Society
Background Dry eye disease (DED) is a common condition that affects tear production and quality. It is classified into aqueous-deficient dry eye and evaporative dry eye, each requiring different treatment approaches.
Eman S.M. Ismail, Amr I. Sharawy, Ahmed A. Shebl   +2 more
doaj   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

The relationship between Graves’ ophthalmopathy and dry eye syndrome

, 2014
Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves&rsquo ...
Sikder S, Selter JH, Gire AI
core  

Topical cyclosporine for severe dry eye disease in liver-transplanted Portuguese patients with familial amyloidotic polyneuropathy (ATTRV30M)

, 2013
PURPOSE. Evaluation of the use of topical cyclosporine eyedrops in the treatment of severe dry eye disease in liver transplanted patients with familial amyloidotic polyneuropathy (FAP) unresponsive to therapy with artificial tears and lacrimal plugs ...
Beirão, I.B., Costa, P.P., Matos, M.E., Beirão, J.M., Torres, P.A.   +4 more
core   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

Effect of a thermo-mechanical action device on symptoms, signs and tear lipid profile in patients with evaporative dry eye disease [PDF]

Bhagyashree Rajesh Rawal, Val Franklin, Marta Blanco‐Vázquez, Shehzad A. Naroo, Sunil Shah, Raquel Gil-Cazorla   +5 more
openalex   +1 more source

Lipid–Polymeric Nanoencapsulation of Standardized Camellia sinensis Extract Enhances Antiangiogenic Activity and Ocular Biocompatibility

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Workflow for the synthesis, characterization, and biological evaluation of lipid–polymeric nanoparticles loaded with a chemically standardized Camellia sinensis extract, showing improved colloidal stability, ocular biocompatibility, and antiangiogenic activity. Created by the authors using BioRender.com.
Sarah Kelly Fernandes, Anízio Bastos de Souza, Líbia Andressa Leandro de Paula, Alessandra Cristine de Souza Matavel, Marcos Paulo Gomes Mol, Mariana de Oliveira Almeida, Vanessa Heloísa Ferreira de Faria, Carolina Paula de Souza Moreira   +7 more
wiley   +1 more source

Prevalence of Dry Eye Disease among Patients Attending an Ophthalmology Outpatient Department

Dry eye disease is a common multifactorial ocular-surface disorder that may cause discomfort, visual disturbance and reduced quality of life. Local evidence regarding its prevalence and associated factors among ophthalmology outpatients in Pakistan ...
Nadeem Ahmad, Asma Mushtaq, Muhammad Salman Nadeem, Rao Muhammad Tariq Aslam, Muhammad Ajmal Chaudhary   +4 more
core   +1 more source

Decoding diversity: Are there patterns in the organization of grooming movements in domestic cats?

Journal of the Experimental Analysis of Behavior, Volume 126, Issue 3, November 2026.
Abstract Grooming is crucial for mammalian health and hygiene, serving diverse functions such as parasite defense, removing dirt, and thermoregulation. Grooming is not purely reactive but integrated into daily routines and regulated endogenously. In rodents, it has been shown to follow a sequential structure with predictable patterns, often interpreted
Anna Hock, Manuela Schmidt
wiley   +1 more source