Extensive cross-reactive T cell epitopes across SARS-CoV-2 Omicron variant spikes with finite immune evasion mutations. [PDF]
Gan M +11 more
europepmc +1 more source
Ethics of Tax Evasion: Evidence from Self-employed Tax-payers' of Dessie Town Administration, Ethiopia [PDF]
Muleye Tarekegn
openalex +1 more source
GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh +8 more
wiley +1 more source
Letter to the editor: LSD1 as an upstream epigenetic regulator of NPM1-PD-L1 axis in hypoxia-driven immune evasion in breast cancer. [PDF]
Iqbal J.
europepmc +1 more source
The Ethics of Tax Evasion: A Case Study of Opinion in Iran
Robert W. McGee, Mahdi Nazemi Ardakani
openalex +1 more source
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira +18 more
wiley +1 more source
SodA promotes immune evasion of <i>Streptococcus suis</i> by suppressing ROS accumulation and GSDMD-mediated mitochondrial disruption in neutrophils. [PDF]
Xie H +12 more
europepmc +1 more source
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
PLAUR, C3, and EMP3 coordinate tumor progression and immune evasion in clear cell renal cell carcinoma. [PDF]
Zi SR, Feng ZY, Dong LS.
europepmc +1 more source

