Results 211 to 220 of about 104,237 (310)

Targeting the neuro-immune crosstalk in breast cancer brain metastases. [PDF]

J Immunother Cancer
Zou Y, Wu J, Yuan Z, He X, Tang H.
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Broad and robust T cell immunity compensates the population immune barrier against antibody-escaping Omicron variants. [PDF]

Front Immunol
Guo Y, Guo P, Tian J, Tuluhongtayi Y, Song R, Gao GF, Zhao X, Liu J.   +7 more
europepmc   +1 more source

EMG‐Driven Telemetry and Inference System for Fish: Pose Reconstruction and Flow Sensing

Advanced Intelligent Systems, EarlyView.
This work introduces an electromyography (EMG)‐driven telemetry framework that reconstructs body pose and infers hydrodynamic conditions in freely swimming fish. A custom 16‐channel archival system records intramuscular EMG, enabling deep‐learning models to decode joint kinematics, classify flow regimes, and reveal channel‐efficient sensing strategies.
Rahdar Hussain Afridi, Waqar Hussain Afridi, Muhammad Hamza, Ahsan Tanveer, Mingxin Wu, Xingwen Zheng, Liang Li, Guangming Xie   +7 more
wiley   +1 more source

Single-cell profiling reveals MIF-mediated immune evasion and CD8 + T cell exhaustion in relapsed multiple myeloma. [PDF]

Clin Exp Med
Ma J, Gao S, Liu S, Chen L, Lin L, Zhang Z, Zhao Z, Li Q.   +7 more
europepmc   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source

Molecular Characterization and Genomic Diversity of SARS-CoV-2 Spike Gene Variants Circulating in Iraq: Mutational Impact on ACE2 Affinity, RBD Immune Escape, and Viral Transmission. [PDF]

Adv Virol
Khudhair AM, Abdulsatar DM, Hatif ST, Ridha DJ, Ali MR, Ali JAAF.   +5 more
europepmc   +1 more source

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan, Yang Liu, Heng‐Huan Lee, Wei Wang, Joseph McIntosh, Yijing Li, Jovanny Vargas, Yue Fei, Sairah Ahmed, Lukas M. Simon, Michael Wang   +10 more
wiley   +1 more source

SLC12A8 Drives Immune Evasion and Metastasis in Luminal B Breast Cancer by Inducing CD8⁺ T-Cell Exhaustion via the TLR Signaling Pathway. [PDF]

Cancer Med
Liu Z, Chen R.
europepmc   +1 more source