Results 81 to 90 of about 630,004 (299)

Towards a research ethics of real-world experimentation with emerging technology

Journal of Responsible Technology
Testing emerging technologies, such as autonomous vehicles, predictive crime analytics, and smart city interventions under real-world conditions is an important strategy for robust and responsible technology development.
Joost Mollen
doaj   +1 more source

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms

Advanced Materials, EarlyView.
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Siwen Sun, Bingbing Sun, Alexander B. Cook, Tania Patiño Padial, Jan C. M. van Hest   +4 more
wiley   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

The concept of succession evasion: An invisible behavior in the organization

Journal of Education and Health Promotion
BACKGROUND: The opposite of succession planning is a new concept called succession evasion; A deep understanding of this concept helps to correct the training process of competent staff in nursing management.
Tahmine Salehi, Mansoureh Ashghali-Farahani, Mohammadsaeed Mirzaee   +2 more
doaj   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Money laundering, embezzlement and tax evasion: a teaching case

Revista Ambiente Contábil
Purpose: This teaching case aims to deepen the knowledge related to money laundering, misappropriation and tax evasion, to encourage the debate in classroom on the accountant's responsibility and ethical dilemma when faced with evidence that their ...
Rodrigo de Souza Gonçalves, Patricia Garone Figueira Falcão, Monick Rodrigues Lima   +2 more
doaj   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Marketing ethics in the wholesale and retail sector: empirical evidence from Ethiopia (a qualitative inquiry)

Cogent Business & Management
Research on the subject of marketing ethics has already been a neglected area. There is a lack of research in the field, especially from the developing world.
Yohannes Workeaferahu Elifneh, Temesgen Abebaw Wonda, Yalew Alemayehu Abbay   +2 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Protocol for purification, crystallization, and structure determination of the mpox virus mRNA cap N7 methyltransferase complex

STAR Protocols
Summary: The mpox virus (MPXV) mRNA cap N7 methyltransferase (RNMT) methylates guanosine at mRNA 5′-cap N7 positions to enable immune evasion. Here, we present a protocol for E1CTD-E12 complex purification and crystallization.
Qingqing Guo, Anke Chen, Jin Ding, Jixi Li   +3 more
doaj   +1 more source