Results 81 to 90 of about 3,052,896 (261)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Twisted modules for tensor product vertex operator superalgebras and permutation automorphisms of odd order [PDF]
, 2013 We construct and classify $(1 \; 2\; \cdots \; k)$-twisted $V^{\otimes k}$-modules for $k$ odd and for $V$ a vertex operator superalgebra. This extends previous results of the author, along with Dong and Mason, classifying all permutation-twisted modules
Barron, Katrina
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Affine difference sets of even order
Journal of Combinatorial Theory, Series A, 1989 Let G be a direct sum of a group of order \(n+1\) and of an Abelian group N of order n-1. If n is even (different from 2), and G admits an affine difference set relative to N then \(n=4k\) and N admits a \((4k-1,4k-1,k-1)\) difference set. Proofs, variations and corollaries are very interesting; for brevity we quote only that there is no nilpotent ...
Arasu, K.T., Jungnickel, Dieter
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Transitive Arcs in Planes of Even Order
European Journal of Combinatorics, 1996 In this paper, the author classifies all arcs in \(\mathrm{PG}(2,q)\), \(q\) even, which are stabilized by a transitive, irreducible (i.e., fixing neither a point nor any line) group \(G\), with the additional assumption that \(G\) does not stabilize a triangle in \(\mathrm{PG}(2,q)\) or in the extension \(\mathrm{PG}(2,q^3)\).
openaire +2 more sources