Results 81 to 90 of about 16,356,505 (288)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Int. Sig. Proc. Workshop on Higher Order Statistics, Chamrouse, France, July 1991.
Direction finding techniques are usually based on the 2ndorder statistics of the received data. In this paper, we propose a MUSIC-like direction finding algorithm which uses a matrix-valued statistic based on the contraction of the 4thorder cumulant ...
Second-Order Versus Fourth-Order
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Oscillation results for even-order quasilinear neutral functional differential equations
In this article, we use the Riccati transformation technique and some inequalities, to establish oscillation theorems for all solutions to even-order quasilinear neutral differential equation $$ Big(ig[ig(x(t)+p(t)x(au(t))ig)^{(n-1)}ig]^gammaBig)' +
Blanka Baculikova +2 more
doaj
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Lower and Upper Solutions for Even Order Boundary Value Problems
In this paper, we prove the existence of solutions of nonlinear boundary value problems of arbitrary even order using the lower and upper solutions method.
Alberto Cabada, Lucía López-Somoza
doaj +1 more source
Generalized quadrangles of even order
AbstractThe quadrangles constructed by Tits using ovoids in finite desarguian planes are shown to be special cases of an abstractly much larger class which also includes a recent generalization of Thas. The general construction is obtained by coordinatizing a quadrangle in terms of a certain group of collineations.
openaire +2 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source

