Results 241 to 250 of about 107,823 (286)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Effects of feeding different baits on the growth of Scylla paramamosain megalopa and the bacterial community in a mariculture system. [PDF]

Sci Rep
Liu Z, Xu L, Qiao G, Li Y, Ma C, Zhang F, Zhao M, Xu J, Ma L, Ma K, Wang W.   +10 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Optimization of DADA2 in QIIME2 for improving fidelity in 16S rRNA V4 amplicon data analysis. [PDF]

Biol Methods Protoc
Singh MG, Wahengbam R.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Objectification of Skin Surface Evenness: In Vivo Evaluation of 300 Women in Relation to Age. [PDF]

J Cosmet Dermatol
Roessle A, Kerscher M.
europepmc   +1 more source

Bumblebee Diversity in Different Habitat Types and Along an Altitudinal Gradient at a Forest-Grassland Ecotone in the East Range of the Qinghai-Tibet Plateau. [PDF]

Insects
Xu X, Bai L, Wang Z, He J, Zhang Y, Li X.   +5 more
europepmc   +1 more source

Injectable Aesthetic Treatments for Improving Facial Skin Quality in Transgender Patients With or Without Gender-Affirming Hormone Therapy. [PDF]

J Cosmet Dermatol
Viscomi B, Goldie K, Kerscher M.
europepmc   +1 more source

Evaluation of riverine macro- and mesoplastic monitoring approaches. [PDF]

Environ Monit Assess
Oswald SB, Vriend P, Ragas AMJ, Schoor MM, Collas FPL.   +4 more
europepmc   +1 more source

Legume cover under <i>Camellia oleifera</i> forests enhances understory biomass carbon storage and soil CO₂ flux but declines soil inorganic carbon storage on a karst steep slope. [PDF]

Front Microbiol
Ding L, Sun H, Long Z, Gao B, Zhou Z, Ye Y, Yang S, Lei X.   +7 more
europepmc   +1 more source