Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Heterogeneity of event-related potentials in a screen-free brain-computer interface
Henrich Kolkhorst +3 more
openalex +1 more source
Age-related Differences in Prestimulus Subsequent Memory Effects Assessed with Event-related Potentials [PDF]
Joshua D. Koen +3 more
openalex +1 more source
An event-related potential study on the information flow during prospective memory interference [PDF]
Poster PresentationBACKGROUND: Electroencephalography (EEG) can examine the temporal sequence of brain activity related to a specific event, which is referred to as event-related potential (ERP).
Cheung, RTF, Gao, J, Mak, W, Wong, W
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Differential effects of mindfulness treatment and mobile neurofeedback on event-related potentials in early posterior negativity in cancer patients: a clinical-experimental parallel group design [PDF]
Madeleine Fink +10 more
openalex +1 more source
Neural correlates of abnormal cognitive conflict resolution in major depression: An event-related potential study [PDF]
Ru-hong Sun +6 more
openalex +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Rapid extraction of category-specific shape statistics: Evidence from event-related potentials
Bria Long +2 more
openalex +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

