Results 61 to 70 of about 2,944,507 (337)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
NAVIGATING HERITAGE: THE DYNAMIC ROLES OF TOUR GUIDES IN KUALA LUMPUR’S HERITAGE WALKING TOURS [PDF]
Geo Journal of Tourism and GeositesHeritage walking tours have gained popularity as tourism offerings, signifying a growing demand for authentic and experiential experiences. The success of these tours depends not only on the historical importance of the sites visited, but also on the ...
Siti Zubaidah Mat TAHIR* +2 more
doaj +1 more source
A New ERA? Marketing and Delivering a User-Education Event for Academic Staff [PDF]
, 2007 Covers project management and innovations introduced in an Information Literacy event for academic staff at Birmingham City University (formerly UCE Birmingham)
Taylor, Darren
core
The development of competitive advantage through sustainable event management [PDF]
, 2011 Purpose: Whilst the debate rages between progressive and destructive considerations of economic development, this paper aims to develop thinking around the sustainable event and its contribution to competitive advantage.
James Musgrave, Stephen Henderson
core +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Gender differences in the implementation of cardiovascular prevention measures after an acute coronary event [PDF]
, 2010 Objective To compare gender-related lifestyle changes and risk factor management after hospitalisation for a coronary event or revascularisation intervention in Europe.
C. Prugger +8 more
core +2 more sources
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Exploring a fuzzy relationships among criteria for the development of community-based tourism in Malaysia: a multi-stakeholder perspective [PDF]
Journal of Humanities and Applied Social SciencesPurpose – The purpose of the study was to identify and analyze the fuzzy relationships among criteria for the development of community-based tourism (CBT) in Malaysia through a multi-stakeholder lens.
Azizah Ismail +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source